Cell Membrane

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What are all cells surrounded by?

a cell membrane

What is the cell membrane also called?

plasma membrane

The cell membrane is the boundary that.....

maintains conditions suitable for the life of the cell by regulating or controlling the passage of materials into and out of the cell

Cell exist in a ____ _______ of shapes.

wide variety

Plant cells are more of what shape, and why?

rigid and box-like, because of the presence of the cell wall

What shapes do animal cells come in, and why?

different shapes, because the fluidity of the cell membrane, which is their only outer structure

What type of membrane is the cell membrane?

semi-permeable

What is a semi-permeable membrane?

it allows certain substances to pass through freely, and restricts others completely

What is the cell membrane mostly made up of?

a bilayer of phospholipids and proteins

bilayer

two layers

What protrudes from the outer surface of the cell membrane?

various carbohydrates

What are the carbohydrates attached to?

proteins or phospholipids

What is a carbohydrate attached to a protein called?

glycoprotein

What is a carbohydrate attached to a phospholipid called?

glycolipid

What do the carbohydrates act as?

receptors

What do carbohydrates receive?

communications from other cells, and they detect chemical changes in their surroundings

What are the major components of the cell membrane?

phospholipids, carbohydrates, and proteins

What are the five functions of the cell membrane?

1. protects the cell by acting as a barrier
2. regulates the transport of substances in and out of the cell
3. receives chemical messengers from other cell
4. acts as a receptor
5. cell mobility, secretions, and absorptions of substances

What two things does the bilayer of phospholipids have?

a hydrophilic head and a hydrophobic tail

What does the hydrophilic head have?

an affinity for water

What does the hydrophobic tail have?

an aversion to water

What does the phospholipids portion of the cells membrane block the passage of?

most of the molecules except water and a few ions

What controls the entry and exit of substances?

the cell membrane

Do proteins play a role in cell recognition?

yes

Who won a Nobel Prize in 1973, and why did they win it?

Joseph Goldstein and Michael Brown, for their discovery of how carbohydrates present on the cell membrane control the level of cholesterol in the human blood

What did Joseph Goldstein and Michael Brown prove?

that glycoproteins protruding from the cell membrane bind to cholesterol particles that circulate in the blood and take them to the cell to make cell membrane

What is cholesterol a key factor in?

the production of hormones like testosterones, progesterone, and bile which, helps in the digestion of fat

What happens if these particles are not taken into the cell?

they could build up in blood vessels and lead to atherosclerosis or narrowing of the arteries which can lead to a heart attack

The greater number of ________ on the cell membrane, the more ___________ containing particles are removed from the blood

glycoprotein, cholesterol

How many glycoproteins on the cell membrane, are in a normal cell?

about 20,000

How many people out of how many people have an abnormally small number of glycoproteins on the cell membrane?

1 in 500 people

If you are one of those people what do you have?

a higher risk of heart attack

Can people with a normal gene have high cholesterol levels?

yes, because when the cell's cholesterol needs are met, the glycoproteins shut off

How do substances move in and out of the cell?

two methods: active and passive transport

What happens during active transport?

substances move against the concentration gradient , from a region of low concentration to a region of high concentration

What does the transportation of molecules require?

energy

Since they move against the concentration gradient during active transport, what is used to move substances?

energy in the form of adenosine tri phosphate

What happens during passive transport?

substances move along the concentration gradient

Why is this type of transport called passive transport?

because energy is not required to move molecules

What is transported against the concentration gradient?

sugar molecules and proteins

Does active transport take place in all cells?

yes, and in some cells it accounts for more than half of the cell's energy expenditure

What is an example of active transport?

the sodium-potassium pump

What happens during this transport?

3 sodium ions are pumped to the outside of the cell for each 2 potassium ions that moves into the cell

What takes place in all human cells? And what cells is especially in

the sodium-potassium pump, especially nerve and muscle cells

What is used to operate the sodium-potassium pump?

one third of the body's energy expenditure

What are two types of active transport that move large molecules across the cell membrane?

exocytosis and endocytosis

Exocytosis

a type of active transport where molecules are exported out of the cell.

Before the molecules are sent out of the cell in exocytosis, they must first be what?

surrounded by a membrane which is called the secretion vesicle

What are some examples of exocytosis?

production and release of materials required for the construction of cell wall, and the production and release of hormones

Endocytosis

a type of active transport were substances are brought into the cell

What are two types of endocytosis?

phagocytosis and pinocytosis

Pinocytosis

it is like cellular drinking

What happens during pinocytosis?

small vesicles form out of the plasma membrane and carry liquid or smaller molecules into the cell from outside

Phagocytosis

equivalent to cellular eating

What happens during phagocytosis?

large molecules or small unicellular organisms are taken into the cell

What is an example of phagocytosis?

the engulfing of bacterium by ameba. the ameba encloses the bacterium and releases enzymes to digest it. the nutrients are absorbed by the ameba, and the unabsorbed waste is discharged by exocytosis

phospholipids

a type of fat

phob

dislike

hydra

water

What is cholesterol used to make?

cell membrane, sex hormones, vitamin D, and bile

What does bile do?

breaks down fat

Where do glycoproteins take cholesterol?

into the cell

What foods are high in potassium

avocados and bananas

How much percent of the cells energy is used to take in potassium?

25%

Where are the beta cells?

in the pancreas

What does APC stand for?

antigen present in cells

What happens when a white blood cell sees a new bacteria?

it will locate, engulf, and disintegrate it slowly, the second time it goes much faster. this is called cell recognition

What is macrophage?

a type of immune cell

gradient

high to low

What are the three types of passive transport?

diffusion, facilitated diffusion, and osmosis

What is diffusion dependent on?

the concentration gradient

Does diffusion need energy?

no

As molecules diffuse from a region of high concentration to a region of low concentration, what happens?

the concentration eventually becomes equal

What happens when concentration evens out?

it reaches equilibrium

equilibrium

equal distribution

What is able to diffuse through the cell membrane?

small molecules such as water, carbon dioxide, and oxygen

What are the factors affecting the rate of diffusion?

*state of matter
*concentration gradient and slope of concentration gradient
*size of molecules
*temperature

What are the three state of matter?

solid, liquid, gas

What are the rates for state of matter from slowest to fastest

*solid
*liquids
*gases

Concentration

the number of particles or ions present in a given space

ions

charged particles

What can the difference in the concentration gradient affect?

the rate of diffusion

The _________ the difference in concentration between the high and low regions, the _________ the molecules will diffuse.

greater, faster

The rate of diffusion increases with what?

an increase in temperature

What happens when heat is applied?

molecules absorb energy and tend to move along the concentration gradient

Where does tea diffuse faster? Hot or Cold water?

hot water

Which molecules diffuse faster?

smaller

Smaller molecules are less likely to what?

collide with opposing larger molecules when they move from a region of more to a region of less

What happens during facilitated diffusion?

substances move along the concentration gradient, however during this, proteins called carrier proteins help in the transport of substances

Why are carrier proteins required during facilitated diffusion?

to move molecules larger than water, carbon dioxide, and oxygen into the cell

What do carrier proteins form?

channels through the cell membrane to facilitate the movement of larger molecules

How do the carrier proteins help?

by increasing the rate of diffusion

Osmosis

the diffusion of water through a semi permeable membrane from a region of high concentration to a region of low concentration

How are water molecules able to move freely through the cell membrane?

because they are very small and can easily pass through

How is the direction of the flow of water determined?

by the amount of solute and solvent present inside and outside of the cell

When water moves into a cell as result of osmosis, it creates pressure within the cell, called what?

osmotic pressure or the force of osmosis

Solutions

homogeneous mixtures of two or more substances

What is a solution usually made up of?

liquids

mixture

the result of the combination of a solvent and solute

solute

the substance that is dissolved in another substance

solvent

the substance in which the solute is dissolved

What is the most common of solvents?

water

What are solutions with water as the solvents called?

aqueous solutions

What is an example of a gas mixing with a liquid?

club soda

What does the amount of solute and solvent present in a solution determine?

the concentration of the solution

During osmosis, the direction of the flow of water depends on what?

the solute/solvent concentration

tonicity

the relative concentration of solute on either side of a cell membrane

Based on tonicity there are three types of solutions, which are:

hypertonic, hypotonic, isotonic

hypertonic solution

a solution that has a high solute concentration and less solvent concentration compared to the outside environment

What is an example of a hypertonic solution?

in a hypertonic salt solution, there is more salt than water

What happens when cells are placed in a hypertonic salt solution?

water molecules will move out of the cell and salt molecules will move into the cell

What is the marine environment?

a hypertonic solution for many organisms

What do these animals have?

special mechanisms to prevent water from leaving their cell and hence prevent dehydration due to loss of water

What do animal cells undergo, when they are placed in a hypertonic solution?

crenation

crenation

where the cell shrivels up as it loses water molecules, and salt molecules enter the cell

What do plant cells undergo, when they are placed in a hypertonic solution?

plasmolysis

plasmolysis

where the plasma membrane pulls away from the cell wall as the cell shrinks due to loss of water

Why does the cell not lose its shape during plasmolysis?

because the cell wall is a rigid structure

hypotonic solution

one that has less solute and more solvent compared to the outside environment

What happens to cells in a hypotonic solution?

they gain water because there is more water outside of the the cell than inside of the cell

What can happen to animal cells in a hypotonic solution?

they can lyse or rupture

Why will the animal cells rupture?

water diffuses into the cell as a result of osmosis, and since animal cells don't have a cell wall, the cell membrane will rupture due to increased osmotic pressure

Where do freshwater organisms live? What is their tendency?

in a hypotonic solution, to gain water

What do these organisms have?

special mechanisms that prevent rupturing

What does the contractile vacuole in freshwater protozan remove?

water that enters the cell

What cells do not tend to rupture?

plant cells, and cells with a cell wall

What is osmotic pressure also called?

turgor pressure

isotonic solution

the concentration of solute is the same on both sides of the membrane, inside and outside of the cell

What happens to a cell that is placed in an isotonic solution?

it neither gains or loses water

red blood cells are very vulnerable to changes in concentration because...

they don't have any mechanism to remove excess water

How can shrinking or bursting of red blood cells be prevented?

blood plasma or the blood fluid should be isotonic

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