| Term | Definition |
| Christopher Columbus | Found a new land when searching for a western route to Asia. |
| Sir Francis Drake | Circumnavigated the globe. |
| Juan Ponce de Leon | Search for the fountain of youth and explorer Florida. |
| Hernando Cortez | Conquered the Aztec empire. |
| Jacques Cartier | Explored far into the St. Lawrence River. |
| Amerigo Vespucci | Realized the "new land" was a brand new continent. America is named after him. |
| Giovanni de Verrazano | 1st person to travel the eastern coast of North America. |
| Vasco de Balboa | 1st European to see the Pacific Ocean. |
| Francisco Pizarro | Conquered the Inca empire. |
| Hernando de Soto | 1st to explore the Mississippi River and Tennessee. |
| Francisco Coronado | Discovered the Grand Canyon. |
| Henry Hudson | Searched for the Northwest Passage and explored the Hudson River. |
| John Cabot | Discovered Newfoundland and Nova Scotia. |
| Ferdinand Magellan | 1st person to said around the world. Named the Pacific Ocean. |