1-18 Cell Wall Synthesis Inhibitors
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16 terms
Terms | Definitions |
|---|---|
 Cefazolin | First Generation Cephalosporin |
| Cephalexin (Keflex) | First Generation Cephalosporin |
| Cefuroxime | Second Generation Cephalosporin |
| Cefoxitin-cephamycins | Second Generation Cephalosporin |
| Cefotetan-cephamycins- MTT* | Second Generation Cephalosporin |
| Cefprozil | Second Generation Cephalosporin |
| *MTT-methylthiotetrazole | Second Generation Cephalosporin |
| Ceftriaxone | Third Generation Cephalosporin |
| Cefotaxime | Third Generation Cephalosporin |
| Ceftazidime | Third Generation Cephalosporin |
| Cefdinir | Third Generation Cephalosporin |
| cefepime | Fourth Generation Cephalosporin |
| Ceftaroline | Fifth Generation Cephalosporin |
| Beta-Lactam Class Includes: | Penicillins Cephalasporins Monobactams Carbapenems *Each of these sublasses differs structurally in the chemical substituents that are attached the to beta lactam ring* |
| Broader Spectra of Action | Ampicillin, Amoxicillin, and especially, Piperacillin, Ticarcillin, Carbenicillin, and Mezlocillin *These are more hydrophilic agents that can diffuse through the thick murein layer of Gram positive bacteria AND tend to pass through to outer membrane pores of Gram negative bacteria much more readily--.: Broader Spectra* |
| Narrower Spectra of Action | Oxacillin, Cloxacillin, dicloxacillin, nafcillin, methicillin, and Penicillin G *These are more hydrophobic agents that can pass through the thick murein layer of Gram positive bacteria (less so than hydrophilic agents) but cannot pass through the outer membrane pores of Gram negative bacteria--.: Narrower Spectra* |
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