endo pharm
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Created by:
sackheimjulia1 on January 18, 2012
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55 terms
Terms | Definitions |
|---|---|
 What two hormones activate JAK2? | GH and prolactin |
| What treats lipodystrophy in HIV and AIDs patients? | GHRH, Somatorelin |
| What drug has an AE of biliary disorders? | SRIH, somatostatin |
| What hormone has an AE of osteoporosis? | Gandorelin |
| How do you distinguish b/w Cushing's and ectopic ACTH secretion? | CRH |
| What is used to determine the cause of hypogonadism? | GnRH |
| Tesamorelin is what kind of ananlog? | GHRH |
| If you give GnRH analogs continuously, you can treat what? | hormone-responsive cancer |
| All hormone analogs, except for Nafarelin, can treat what? | prostate cancer |
| Nafarelin is used for what? | intranasally for endometriosis |
| what is used intranasally for endometriosis | nafareling (GnRH analog) |
| three GnRH antagonists | cetrorelix, ganirelix, degarelix |
| What is used to treat infertility due to premature LH surges? | cetrorelix and ganirelix (GnRH antagonists) |
| What is degarelix used for? | advanced prostate cancer |
| Octreotide is what kind of analog? | SRIH |
| SRIH clinical uses | not used, because short half life |
| What is used to treat Acromegaly, VIPomas, Carcinoid tumors? | SRIH analogs. don't cause hyperglycemia |
| What treats bleeding due to esophageal varices? | octreotide |
| WHat kind of drug is bromocriptine? | D2 agonist |
| What are bromocriptine and cabergoline used for? | hyperprolactinemia, prolactinomas |
| What drug causes psychiatric disturbances? | PIH analogs |
| two dopamine receptor antagonists | phenothiazine haloperidal |
| FSH is used for | infertility |
| AE of FSH | ovarian enlargement, mult births, gynecomastia |
| LH is used for | infertility |
| What is used for cryptorchidism? | HcG |
| What is HcG used for | infertility, hypogonadism, cryptochorchidism |
| luptropin alfa is used for | infertility in females due to hypogonadism. HcG analog |
| Contraindications to LH analogs | precocious puberty, androgen dependent neoplasm |
| precocious puberty and androgen dependent neoplasms are contraindications to what | LH |
| What is used to treat AIDs assoc muscle wasting? | GH |
| What is used ot treat Short Bowel Syndrome? | GH |
| GH is contraidicated in who | kids whose long bones have closed |
| mecasermin is what kind of durg | recominant IGF-1 |
| AE of mescamerin | hypoglycemia |
| what kind of drug is pegcisomant | GH antagonist |
| Pegvisomant is used for | acromegaly |
| What drug can increase hepatic enzymes and cause hepatotoxicty? | Pegvisomant |
| what is used to differentiate between primary and secondary hypothyroidism? | thyrotropin |
| what kind of drug is thyrotropin | TSH |
| Thyrotropin alpha is used for what? | thyroid tumor recurrence. tells you if all of cancer has been removed |
| cosyntropin is what kind of drug | ACTH |
| cosynotropin is used to differentiate between what | primary and secondary hypoadrenocorticosteroidism (addison's) |
| What can you use in place of FSH | menotropins |
| only peptide given by mouth | desmopressin |
| Vasopressin V2 effects | increase perm of water. stim release of vWF and VIII |
| V1 effects | vasoconstriction |
| Conivaptan is what kind of drug | vasopressin antag |
| Tolvaptan is what kind of drug | vasopressin antag |
| dual v1 and v2 antag | conivaptan |
| selective V2 antag that can be used in heart failyre | tolvaptan |
| Use vasopressin antag when | hyponatremic states |
| What is used to treat Diabetes insipidus and noctural diuresis? | desmospressin acetate |
| what can treat VWF and VIII def | Desmopressin acetate |
| OCP work how | estrogen blocks ovulation through neg feedback by blocking release of LH |
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