Alzheimers Dis.
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22 terms
Terms | Definitions |
|---|---|
What % of cases of dementia among the elderly is due to Alzheimer's? | 60 - 80% of cases of dementia among the elderly |
Whats the incidence of elderly 85 and over? | 85 and over: >8% ( |
AD patients live how many years after being diagnosed? | 8-10 |
Name the 3 Stages?: | Stages: Mild, Moderate, Severe |
Alzheimers Association categorizes how many stages: | 7 |
Stage 1? | no impairment |
Stage 2? | very mild decline |
stage 3? | mild decline |
Stage 4? | moderate decline (early stage) |
Stage5? | moderately severe decline (midstage) |
Stage 6? | severe decline (midstage) |
Stage 7? | very severe decline (late stage) |
Mild AD? | - Loses zest for life; does not start anything, Loses recent memory, Has difficulty with new learning, Difficulty finding words, Easily loses way going to familiar places, Asks repetitive questions, Loses/ misplaces posessions, Eating abnormalities |
Moderate AD? | Changes in behavior, appearance, hygiene and sleep become more noticeable, Confusion about people's identities - and which objects, Continuously repeats stories, favorite words, statements, Fabricates stories to fill in memory gaps, Abnormal behaviors: accusing, threatening, cursing, fidgeting, paranoia, physical aggression, inappropriate sexual behaviors; Difficulty positioning body for self-care tasks, |
Severe Ad? | Ceases to recognize self or close family, Severe language impairments: may groan, scream or mumble loudly, Severe eating impairments : refusal, choking, impaired swallow, Compulsive behaviors: repeated vocalizations, patting objects, Incontinence, Weight loss, Intolerance to touch , Unable to walk/ frequent falls, Ideational apraxia, Total assistance for ADLs, Seizures |
AD PATHOLOGY? | Intracellular neurofibrillary tangles and loss of neurons, Formation of neuritic plaques, Extracellular deposition of amyloid-beta protein |
Most significant cellular changes occur where? | hippocampus |
neuroanatomical changes in AD? | decrease in cortical mass in hippocampus and prefrontal cortex and enlargements in ventricles |
Mini Mental State Examination looks at? | orientation, registration, attn. and calculation, recall, and language |
high likelihood of dementia is if you score what or less on MMSE? | 23 or less |
Medical Tx is what? | Symptom-based at this time; Antipsychotic drugs, Antidepressant drugs: SSRIs preferred, and behavioral interventions, CHOLINESTERASE INHIBITORS to increase Ach, |
MEDICATIONS TO TREAT memory impairment? | CHOLINESTERASE INHIBITORS to increase Ach during mild and moderate stages; NAMENDA an NMDA antagonist for moderate to severe AD and it may delay progression of symptoms |
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