Biochem Unit 2 Eb2834
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19 terms
Terms | Definitions |
|---|---|
 PDH E1 | Pyruvate DH + TPP |
| PDH E2 | Dihydrolipoyl Transacetylase + Lipoic acid (lipoate) |
| PDH E3 | Dihydrolipoyl DH + FAD |
| Permanent cofactors of PDH | TPP Lipoate FAD |
| Non-permanent cofactors of PDH | CoA-SH NAD+ |
| Inhibitors of PDH (4) | ATP Acetyl-CoA NADH Fatty Acids |
| Stimulators of PDH (4) | AMP CoA NAD+ Ca2+ |
| Inhibitors of Citrate Synthase (4) | NADH Succinyl-CoA Citrate ATP |
| Stimulator of citrate synthase (1) | ADP |
| Inhibitors of Isocitrate Dehydrogenase (2) | ATP NADH |
| Stimulators of isocitrate dehydrogenase (2) | Ca2+ ADP |
| Inhibitors of a-ketoglutarate dehydrogenase complex (2) | succinyl-CoA NADH |
| Stimulators of a-ketoglutarate DH complex (1) | Ca2+ |
| Redox Carriers | Nicotinamide and Flavin e- carriers Ubiquinone Heme Iron-sulfur clusters |
| 3 Fates for Glucose | Storage in glycogen Oxidation to ribose-5-phosphate Oxidation to pyruvate |
| Two in vivo sources of glucose | Mobilization from glycogen REduciton of non-carb precursors to gluconeogenic substrates |
| Carbon sources for gluconeogenesis | Lactate Amino acids (alanine) Glycerol Proprionate |
| 3 Tissues active in gluconeogenesis | Liver (principal) Kidney Cortex Skeletal Muscle |
| Reactive Oxygen Species | Singlet oxygen Superoxide radical anion Hydrogen peroxide Lipid peroxyl radical hydroxyl radical |
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