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5 Written questions

5 Matching questions

  1. PENICILLIN G or V
  2. GENTAMICIN
  3. CIPROFLOXACIN Nursing implications -
  4. CEFUROXIME
  5. Oxacillin
  1. a PO on empty stomach ; intermittent infusion; observe for s/s of anayphylaxis, monitor bowel function
  2. b Action - Binds to bacterial cell wall membrane, causing cell death; Bactericidal action against susceptible bacteria. Similar to that of first-generation cephalosporins but has increased activity against several other gram-negative pathogens including. Haemophilus influenzae (including B -lactamase-producing strains) Haemophilus parainfluenzae
    › Escherichia coli.
    › Klebsiella pneumoniae.
    › Neisseria .
    › Proteus.
    › Moraxella catarrhalis.
    › Borrelia burgdorferi.

    Use - Treatment of. Respiratory tract infections, Skin and skin structure infections, Bone and joint infections (IV), Urinary tract infections, Gynecological infections, Septicemia (IV), Otitis media (PO), Meningitis (IV), Lyme disease (PO); Perioperative prophylaxis (IV).

    Side Effect - d/n/v/r; urticaria, diaper dermatitis, seizures (high doses) pseudomembranous colitis, bleeding eosinophilia, hemolytic anemia, leucopenia, Pain @ IM site, phlebitis @ IV site, allergic reactions including anaphylaxis, superinfection

    Contraindictions - Hypersensitivity to cephalosporins. Serious hypersensitivity to penicillins

    Nursing implications - PO, admin with food; IM/IV, Direct IV, Intermittent infusion

    Trade / Generic Name - Ceftin, zinacef

    Classification - 2nd generation cephalosporins; anti- infectives

    Dosage: PO 250mg q 12hrs- Pharyngitis/tonsillitis, UTI
    250mg-500mg q12- Bronchitis
    IM 750mg q 8hrs UTI
    1.5 q 6hrs- Life threatening infections
  3. c Action - Inhibits protein synthesis in bacteria at level of 30S ribosome; Bactericidal action; Notable for activity against. › Pseudomonas aeruginosa.
    › Klebsiella pneumoniae.
    › Escherichia coli.
    › Proteus.
    › Serratia.
    › Acinetobacter.
    › Staphylococcus aureus.
    In treatment of enterococcal infections, synergy with a penicillin is required.

    Use- Treatment of serious gram-negative bacterial infections and infections caused by staphylococci when penicillins or other less toxic drugs are contraindicated.
    • In combination with other agents in the management of serious enterococcal infections.
    • Prevention of infective endocarditis.
    • Topical, Ophth: Treatment of localized infections due to susceptible organisms.

    Side Effect - ataxia, vertigo, ototoxicity(vestibulare & cochlear) nephrotoxiticy, muscle paralysis(high parenteral doses); hybersensitivyt reactions

    Contraindictions - Hypersensitivity to gentamicin or other aminoglycosides.
    • Most parenteral products contain bisulfites and should be avoided in patients with known intolerance.
    • Pedi: Products containing benzyl alcohol should be avoided in neonates.

    Nursing implications - Keep patient well Hydrated, IM; Intermittent infusion; topical
    Evaluate 8th cranial nerve function, I/O, assess for superinfection

    Trade / Generic Name - Garamycin, G-Mycin, Jenamicin

    Classification - Aminoglycosides; anti-infectives

    Dosage: IM/IV 1-2mg/kg q 8hrs up to 6mg/kg a day in 3 divided doses
  4. d Action - bind to bacterial cell wall, resulting in cell death; gram positive & negative

    Use - Pneumocoocal pneumonia; streptoccocal pharyngitis, syphilis, Gonorrhea strains, enterococcal infection; Prevention of rheumatic fever

    Side Effect - Seizures, epigastric distress, interstitial Nephritis , Urticaria

    Contraindications - Previous hypersensitivity to penicillin

    Nursing Implications - Administer IV / IM = Penicillin G; PO = Penicillin V ; Observe for

    Trade Name/ Generic - Pfizerpen; Wycillin; Bicillin L-A, Permapen

    Classification: Penicillins, anti-infectives
  5. e Action - bind to bacterial cell wall, leading to cell death; Inactivated by penicillinase enzyme; Gram positive aerobic cocci

    Use - Respiratory tract infections, sinusitis, skin & skin structure infections , bone & joint infections, urinary tract infection , endocardistis, bacterium, meningitis

    Side Effects - seizures, Nephritis, urticaria, allergic reaction ; Pain @ IM Site

    Contraindictions - Previous hypersensitivity to penicillin; Cross sensitivity with cephaloporins & beta lactam antibiotics

    Nursing Implications - IM, IV, & intermittent Infusion; Observe for signs & symptoms of anaphylaxis

    Trade / Generic Name - Bactocill

    Classification: Penicillinase resistant penicillins, Anti-infectives

    Dosage:Moderate Infection 250-500mg IM/IV q 4-6hrs
    Serve Infection 1-2gm IM/IV q 4-6hrs

5 Multiple choice questions

  1. Treatment of serious gram-negative bacterial infections and infections caused by staphylococci when penicillins or other less toxic drugs are contraindicated.
    • In combination with other agents in the management of serious enterococcal infections.
    • Prevention of infective endocarditis.
    • Topical, Ophth: Treatment of localized infections due to susceptible organisms.
  2. Action - Binds to bacterial cell wall membrane, causing cell death; Bactericidal action against susceptible bacteria; Active against many gram-positive cocci including
  3. - d/v/n/r urticaria, seizures(high doses) pseudomembranous colitis, hepatic dysfunction, vaginal candidiasis, blood dycrasias, allergic reactions including anaphylaxis & serum sickness, superinfection
  4. Nursing implications - IM / IV; observe for s/s of anaphylaxis & monitor bowel function
  5. - d/n/v/r; seizures(high doses), pseudomembranous colitis, cramps, Stevens-Johnson Syndrome, Pruritis, urticaria, leucopenia, neutropenia, thrombocytopenia, pain at IM site, phlebitis at IV site, anaphylaxis serum sickness, superinfection

5 True/False questions

  1. OXACILLIN Contraindictions -Hypersensitivity to penicillins (cross-sensitivity exists to cephalosporins and other beta-lactams). Tablets for oral suspension (DisperMox) contain aspartame

          

  2. CIPROFLOXACIN usePO, IV: Treatment of the following bacterial infections. › Urinary tract infections, including cystitis, pyelonephritis, and prostatitis.
    › Respiratory tract infections, including acute sinusitis, acute exacerbations of chronic bronchitis, community-acquired pneumonia, and nosocomial pneumonia.
    › Uncomplicated and complicated skin and skin structure infections.
    • Post-exposure treatment of inhalational anthrax

          

  3. CEFUROXIME Nursing implications -Nursing implications - IM / IV; observe for s/s of anaphylaxis & monitor bowel function

          

  4. AUGMENTIN (Amoxicillin/Clavulanate) Action-Binds to bacterial cell wall, causing cell death; spectrum of amoxicillin is broader than penicillin. Clavulanate resists action of beta-lactamase, an enzyme produced by bacteria that is capable of inactivating some penicillins; Bactericidal action against susceptible bacteria

          

  5. PIPERACILLIN side effects are- seizures, Nephritis, urticaria, allergic reaction ; Pain @ IM Site

          

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