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5 Written questions

5 Matching questions

  1. CEFTRIAXONE use
  2. LEVOFLOXACIN Nursing implications
  3. CIPROFLOXACIN
  4. CEFUROXIME
  5. AUGMENTIN (Amoxicillin/Clavulanate) Nursing implications -
  1. a Action - Binds to bacterial cell wall membrane, causing cell death; Bactericidal action against susceptible bacteria. Similar to that of first-generation cephalosporins but has increased activity against several other gram-negative pathogens including. Haemophilus influenzae (including B -lactamase-producing strains) Haemophilus parainfluenzae
    › Escherichia coli.
    › Klebsiella pneumoniae.
    › Neisseria .
    › Proteus.
    › Moraxella catarrhalis.
    › Borrelia burgdorferi.

    Use - Treatment of. Respiratory tract infections, Skin and skin structure infections, Bone and joint infections (IV), Urinary tract infections, Gynecological infections, Septicemia (IV), Otitis media (PO), Meningitis (IV), Lyme disease (PO); Perioperative prophylaxis (IV).

    Side Effect - d/n/v/r; urticaria, diaper dermatitis, seizures (high doses) pseudomembranous colitis, bleeding eosinophilia, hemolytic anemia, leucopenia, Pain @ IM site, phlebitis @ IV site, allergic reactions including anaphylaxis, superinfection

    Contraindictions - Hypersensitivity to cephalosporins. Serious hypersensitivity to penicillins

    Nursing implications - PO, admin with food; IM/IV, Direct IV, Intermittent infusion

    Trade / Generic Name - Ceftin, zinacef

    Classification - 2nd generation cephalosporins; anti- infectives

    Dosage: PO 250mg q 12hrs- Pharyngitis/tonsillitis, UTI
    250mg-500mg q12- Bronchitis
    IM 750mg q 8hrs UTI
    1.5 q 6hrs- Life threatening infections
  2. b Treatment of. Skin and skin structure infections.
    › Bone and joint infections.
    › Complicated and uncomplicated urinary tract infections.
    › Uncomplicated gynecological infections including gonorrhea.
    › Lower respiratory tract infections.
    › Intra-abdominal infections.
    › Septicemia.
    › Meningitis.
    › Otitis media.
    Perioperative prophylaxis
  3. c Action - Inhibits bacterial DNA synthesis by inhibiting DNA gyrase enzyme.; Death of susceptible bacteria; Active against gram-positive pathogens, including. › Staphylococcus aureus.
    › Staphylococcus epidermidis.
    › Staphylococcus saprophyticus.
    › Streptococcus pyogenes.
    › Streptococcus pneumoniae.
    › Enterococcus faecalis.
    › Bacillus anthracis (anthrax).
    • Gram-negative spectrum notable for activity against. › Escherichia coli.
    › Klebsiella pneumoniae.
    › Enterobacter cloacae.
    › Salmonella typhi.
    › Shigella spp.
    › Proteus mirabilis.
    › Proteus vulgaris.
    › Providencia stuartii.
    › Providencia rettgeri.
    › Morganella morganii.
    › Pseudomonas aeruginosa.
    › Serratia marcescens.
    › Haemophilus influenzae.
    › Neisseria gonorrhoeae.
    › Moraxella catarrhalis.
    › Campylobacter jejuni.

    Use- PO, IV: Treatment of the following bacterial infections. › Urinary tract and gynecologic infections, including cystitis, gonorrhea, and prostatitis.
    › Respiratory tract infections including acute sinusitis, acute exacerbations of chronic bronchitis, and pneumonia.
    › Skin and skin structure infections .
    › Bone and joint infections .
    › Infectious diarrhea .
    › Complicated intra-abdominal infections (with metronidazole).
    › Typhoid fever.
    • Post-exposure prophylaxis of inhalational anthrax.
    • Cutaneous anthrax.

    Side Effect - Seizures, dizziness, drowsiness, headache, insomnia, agitation, confusion, d/n/r , pseudomembranous colitis, abdominal pain, abnormal liver enzymes, vaginitis, photosensitivity, hyperglycemia, hypoglycemia, eosinophilia, phlebitits at IV site, tendinitis, tendon rupture, peripheral neuropathy, anaphylaxis

    Contraindictions - Hypersensitivity (cross-sensitivity within class may exist).
    • OB: Do not use unless potential benefit outweighs potential fetal risk.
    • Pedi: Use only for treatment of anthrax and complicated urinary tract infections in children 1-17 years due to possible arthropathy.

    Nursing implications - PO on empty stomach ; intermittent infusion; observe for s/s of anayphylaxis, monitor bowel function

    Trade / Generic Name - Cipro, Cipro XR, Proquin XR

    Classification - Fluoroquinolones; anti-infectives

    Dosage: PO 500-750 mg q 12hrs
    IV 400 mg q 12 hrs
  4. d PO; intermittent infusion
  5. e Nursing implications - PO(Administer at the start of a meal to enhance absorption and to decrease GI side effects. Do not administer with high fat meals; clavulanate absorption is decreased.)

5 Multiple choice questions

  1. Seizures, dizziness, drowsiness, headache, insomnia, agitation, confusion, d/n/r , pseudomembranous colitis, abdominal pain, abnormal liver enzymes, vaginitis, photosensitivity, hyperglycemia, hypoglycemia, eosinophilia, phlebitits at IV site, tendinitis, tendon rupture, peripheral neuropathy, anaphylaxis
  2. IM, IV, & intermittent Infusion; Observe for signs & symptoms of anaphylaxis
  3. - d/v/n/r urticaria, seizures(high doses) pseudomembranous colitis, hepatic dysfunction, vaginal candidiasis, blood dycrasias, allergic reactions including anaphylaxis & serum sickness, superinfection
  4. Pneumocoocal pneumonia; streptoccocal pharyngitis, syphilis, Gonorrhea strains, enterococcal infection; Prevention of rheumatic fever
  5. Treatment of the following infections due to susceptible organisms, Skin and skin structure infections (including burn wounds). Pneumonia, Urinary tract infections, Biliary tract infections, Genital infections, Bone and joint infections, Septicemia, Bacterial endocarditis prophylaxis for dental and upper respiratory procedures; Perioperative prophylaxis

5 True/False questions

  1. CEFUROXIME UseAction - Binds to bacterial cell wall membrane, causing cell death; Bactericidal action against susceptible bacteria. Similar to that of first-generation cephalosporins but has increased activity against several other gram-negative pathogens including. Haemophilus influenzae (including B -lactamase-producing strains) Haemophilus parainfluenzae
    › Escherichia coli.
    › Klebsiella pneumoniae.
    › Neisseria .
    › Proteus.
    › Moraxella catarrhalis.
    › Borrelia burgdorferi.

    Use - Treatment of. Respiratory tract infections, Skin and skin structure infections, Bone and joint infections (IV), Urinary tract infections, Gynecological infections, Septicemia (IV), Otitis media (PO), Meningitis (IV), Lyme disease (PO); Perioperative prophylaxis (IV).

    Side Effect - d/n/v/r; urticaria, diaper dermatitis, seizures (high doses) pseudomembranous colitis, bleeding eosinophilia, hemolytic anemia, leucopenia, Pain @ IM site, phlebitis @ IV site, allergic reactions including anaphylaxis, superinfection

    Contraindictions - Hypersensitivity to cephalosporins. Serious hypersensitivity to penicillins

    Nursing implications - PO, admin with food; IM/IV, Direct IV, Intermittent infusion

    Trade / Generic Name - Ceftin, zinacef

    Classification - 2nd generation cephalosporins; anti- infectives

    Dosage: PO 250mg q 12hrs- Pharyngitis/tonsillitis, UTI
    250mg-500mg q12- Bronchitis
    IM 750mg q 8hrs UTI
    1.5 q 6hrs- Life threatening infections

          

  2. PENICILLIN G or V Contraindications -Previous hypersensitivity to penicillin

          

  3. AMPICILLIN Contraindictions -hypersensitivity to penicillins

          

  4. CEFUROXIME Action -Binds to bacterial cell wall membrane, causing cell death; Bactericidal action against susceptible bacteria. Similar to that of first-generation cephalosporins but has increased activity against several other gram-negative pathogens

          

  5. CEFUROXIME Contraindictions -Hypersensitivity to cephalosporins.
    • Serious hypersensitivity to penicillins.
    • Pedi: Neonates 28 days (use in hyperbilirubinemic neonates may lead to kernicterus).
    • Pedi: Neonates 28 days requiring calcium-containing IV solutions ( risk of precipitation formation).

          

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