← Antobiotic Drugs Test
5 Written Questions
5 Matching Questions
- AMOXICILLIN Nursing implications -
- CEFAZOLIN use
- CEFAZOLIN Contraindictions -
- PIPERACILLIN Contraindictions -
- a Hypersensitivity to penicillins, beta-lactams, cephalosporins, or tazobactam (cross-sensitivity may occur
- b Action - Binds to the bacterial cell wall membrane, causing cell death; Bactericidal action against susceptible bacteria; Similar to that of second-generation cephalosporins, but activity against staphylococci is less, while activity against gram-negative pathogens is greater, even for organisms resistant to first- and second-generation agents. Notable is increased action against. › Acinetobacter.
› Haemophilus influenzae (including -lactamase-producing strains).
› Haemophilus parainfluenzae.
› Escherichia coli.
› Klebsiella pneumoniae.
› Morganella morganii.
› Moraxella catarrhalis.
Has some activity against anaerobes, includingBacteroides fragilis .
Use - Treatment of. › Skin and skin structure infections.
› Bone and joint infections.
› Complicated and uncomplicated urinary tract infections.
› Uncomplicated gynecological infections including gonorrhea.
› Lower respiratory tract infections.
› Intra-abdominal infections.
› Otitis media.
Side Effect - sezures (High doses), pseudomembranous colitis, d/, cholelithaiasis, gallbladder sludging, rashes, urticaria, bleeding, eosinophilia, hemolytic anemia, leucopenia, thrombocytosis, pain @ IM site, phlebitis at IV site, anaphylaxis, superinfection
Contraindictions - Hypersensitivity to cephalosporins.
• Serious hypersensitivity to penicillins.
• Pedi: Neonates 28 days (use in hyperbilirubinemic neonates may lead to kernicterus).
• Pedi: Neonates 28 days requiring calcium-containing IV solutions ( risk of precipitation formation).
Nursing implications- IV; IM; Intermittent infusion
Trade / Generic Name - Rocephin
Classification - 3rd Generation cephalosporins; anti-infectives
Dosage: IM/IV 1-2gm q 12-24hr most infections
2gm q 12hrs
- c PO ; Less GI distress than Ampilicin; s/s anaphylaxis, Monitor bowl function
- d Treatment of the following infections due to susceptible organisms, Skin and skin structure infections (including burn wounds). Pneumonia, Urinary tract infections, Biliary tract infections, Genital infections, Bone and joint infections, Septicemia, Bacterial endocarditis prophylaxis for dental and upper respiratory procedures; Perioperative prophylaxis
- e Contraindictions - Hypersensitivity to cephalosporins, Serious hypersensitivity to penicillins
5 Multiple Choice Questions
- Previous hypersensitivity to penicillin
- Skin and skin structure infection Otitis media, Sinusitis Respiratory tract infections, Genitourinary tract infections.
- IM, IV, & intermittent Infusion; Observe for signs & symptoms of anaphylaxis
- PO on empty stomach ; intermittent infusion; observe for s/s of anayphylaxis, monitor bowel function
- Action - Binds to bacterial cell wall membrane, causing cell death. Spectrum is extended compared with other penicillins; Death of susceptible bacteria( active against piperacillin-resistant, beta-lactamase-producing)
Use - Appendicitis and peritonitis, Skin and skin structure infections, Gynecologic infections, Community-acquired and nosocomial pneumonia caused by piperacillin-resistant, beta-lactamase-producing bacteria.
Side Effect - d/n/v/r/ constipation, drug induced hepatitis, confusion dizziness, headache, insomnia, lethargy, interstitial nephritis, bleeding ,leucopenia, neutropenia, thrombocytopenia, pain, phlebitis at IV site; hypersensitivity reactions, serum sickness, fever(increase in cystic fibrosis patients), superinfection
Contraindictions - Hypersensitivity to penicillins, beta-lactams, cephalosporins, or tazobactam (cross-sensitivity may occur
Nursing implications - intermittent infusion ; s/s of anaphylaxis
Trade / Generic Name - Zosyn
Classification - extended spectrum penicillins; anti infectives
Dosage: Most infections 3.375gm q 6hrs
4.5 gm q 6hrs
5 True/False Questions
CEFUROXIME Use → Use - Treatment of. Respiratory tract infections, Skin and skin structure infections, Bone and joint infections (IV), Urinary tract infections, Gynecological infections, Septicemia (IV), Otitis media (PO), Meningitis (IV), Lyme disease (PO); Perioperative prophylaxis (IV).
CEFUROXIME Action - → Action - Binds to bacterial cell wall membrane, causing cell death; Bactericidal action against susceptible bacteria; Active against many gram-positive cocci including
PIPERACILLIN Action - → bind to bacterial cell wall, leading to cell death; Inactivated by penicillinase enzyme; Gram positive aerobic cocci
PENICILLIN G or V Nursing Implications → - Administer IV / IM = Penicillin G; PO = Penicillin V ; Observe for s/s anaphalxis
PENICILLIN G or V side effects are → Seizures, epigastric distress, interstitial Nephritis , Urticaria