5 Written Questions

1. Yes, generally crossovers inhibit other crossover events a.k.a. crossover interference
2. at the 4 chromatid stage of meiosis
3. Spo11
   Mre11
4. Gametic ratio 1:1:1:1
   50% recombination
5. linked genes

5 Matching Questions

1. Law of independent Assortment
2. Linked alleles tend to be inherited
3. Mutability
4. Two equally frequent non-recombinant classes totaling more than 50%
   Two equally frequent recombinant classes totaling less than 50%
5. The location of genes on a given chromosome influences?

1. a linkage
2. b DNA must be able to change.
3. c as a package
4. d Inheritance
   linked genes are usually inherited together
5. e Inheritance of one trait is independent of other inherited traits

5 Multiple Choice Questions

1. A dihybrid test cross between a tester parent with only recessive alleles (yyrr) by an F1 generation dihybrid (YyRr) yyrr x YyRr
   1. How do you test for recombination frequency?
   2. How would you test for gametic ratio?
   3. Law of equal segregation
   4. How do you determine linkage?
2. Testcross
   1. Law of equal segregation
   2. How would you test for gametic ratio?
   3. How do you determine linkage?
   4. How do you test for recombination frequency?
3. Yes, but they are exact copies of each so there is no exchange in genetic information
   1. The crossover conformation is called a
   2. When does crossing over take place?
   3. Does crossing over occur between sister chromatids?
   4. How would you test for gametic ratio?
4. Gene(s) associated with a given trait. Essentially a fixed charactered of an organism (except for rare mutations)
   1. genotype
   2. Phenotype
   3. Translation
   4. Linkage
5. Perform a testcross
   1. How do you determine linkage?
   2. Developmental noise
   3. How would you test for gametic ratio?
   4. Genes determine Phenotype

5 True/False Questions

1. Linkage → When 2 genes are close together on the same chromosome (linked by the DNA between them), they may not sort independently.

   True        False

2. Deviations are usually help in check by? → using the recombination frequency to estimate the distance (cM) between genes
   RF 10% then genes are 10 cM apart

   True        False

3. Does a recombinant frequency less than 50% confirm linkage? → linked genes

   True        False

4. What are you looking for in a testcross when investigating linkage? → Gametic ratio 1:1:1:1
   50% recombination

   True        False

5. Number of facets in the left eye ≠ → number of facets in the right eye of the same fly

   True        False