Chapter 11 Physiology of the Muscular System

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nathan_sweat  on February 1, 2012

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IDC Class 12010

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Chapter 11 Physiology of the Muscular System

What are the general functions of Muscles?
-Movement
-Posture
-Heat Production
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What are the general functions of Muscles? -Movement
-Posture
-Heat Production
What are the characteristics of Muscle tissues? -Excitablility
-Contractility
-Extensibility
What is the ability of the muscle to be stimulated (respond to nerve impulses)? Excitability
What is the ability of the muscle to contract or shorten? Contractility
What is the ability of the muscle to extend or stretch? Extensibility
What is the plasma membrane of muscle fiber? Sarcolemma
What is the cytoplasm of the muscle fiber? Sacroplasm
What organelle is the "powerhouse of the cell"? Mitochondria
Muscle cells are called fibers because of what? Their threadlike shape
What is the network of tubules and sacs found within muscle fibers that temporarily stores Ca ions? Sarcoplasmic Reticulum (SR)
What part of the muscle cell temporarily stores Ca ions? Sarcoplasmic Reticulum
What extend transversely across the sarcoplasm at right angles to long axis of muscle fiber formed by inward extensions of sarcolemma? T Tubules
What allow electrical signals, or impulses traveling along the sarcolemma to move deeper into the cell? T Tubules
What is a triplet of tubules; a T tubule sandwiched between two sacs of sarcoplasmic reticulum? Triad
What allows the electrical impulse traveling along a T Tubule to stimulate the membranes of adjacent sacs of the Sarcoplasmic Reticulum? Triad
What are the bundles of very fine cytoskeletal filaments that extend lengthwise along skeletal muscle fiber and almost fill the sarcoplasm? Myofibrils
What are the fine fibers that make up Myofibrils? Myofilaments
What are the two types of Myofilaments? -Thick
-Thin
What are the protiens that make up the thick Myofilaments? Myosin
What are the protiens that make up the thin Myofilaments? -Actin
-Tropomyosin
-Troponin
What is the basic contractile unit of the muscle cell? Sacrocomere
What is located in the middle of the thin Myofilament? Z Line (Z disk)
What is a segment of the myofibril between two sucessive Z lines? Sarcomere
What is the segment of sarcomere that runs the entire length of the thick filaments? A band
What is the segment of sacromere that includes the Z line and ends of the thin filaments where they don't overlap the thick filaments? I band
What is another name for muscle? Straiated Muscle
Each myofibril consists of approximately how many sarcomeres? 15,000
What does myosin make up? Thick filament
What protein is chemically attracted to the Actin? Myosin
What is the area where the Myosin "heads" are attached to actin? Cross bridges
What is the globular protein that forms two fibrous strands that twist around each other to form the bulk of thin filament? Actin
What protein blocks the active sites on the Actin molecules? Tropomyosin
What protein holds the tropomyosin molecules in place? Troponin
What part of the Myosin is atracted (towards) the Actin? Myosin "heads"
What binds with Troponin which causes the troponin to release the tropomyosin? Calcium
When does contraction begin? When Ca++ binds to Troponin
Skeletal muscle fiber remains at rest until stimulated by what? Motor neuron
What is the special type of nerve cell that stimulates skeletal muscle fibers? Motor Neuron
Where do Motor Neuron's connect? To the Sarcolemma of a muscle fiber at a folded motor endplate
What is the area where the motor neurons connect to the carcolemma at the motor endplate? Neuromuscular junction
What is the junction where the motor neuron connects to the sarcolemma of a muscle fiber at a folded motor endplate? Neuromuscular Junction (NMJ)
What is the neurotransmitter that is released into the synaptic cleft that diffuses across gap, stimulates receptros, and initiates impulse in sarcolemma? Acetylcholine
Nerve impulses travels over the Sarcolemma and inward along what? T Tubules
What releases the calcium ions from the SR? The nerve impulses that traveled along the sacrolemma and inward along the T tubules
What binds to Troponin causing Tropomyosin to shift and expose active sites on Actin? Calcium
What happens when the active sites on actin are exposed? Myosin heads bind to the Actin
What is it called when the thick filaments pull on the thin filaments? Sliding filament model
Muscle fibers usually contract how much of their starting length?? 80%
What happens when Ca++ ions are removed from troponin molecules? Shuts down contraction
Where do Ca++ ions go when released from the troponin molecules? Ca++ ions are pumped back into the sacks of the Sarcoplasmic Reticulum
What are the 2 types of energy sources muscle uses for contraction? -ATP
-Creatine Phosphate
There is only enough ATP in muscle fiber for how long of maximum contraction? 2-4 seconds
What is the backup energy supply for ATP? Creatine Phosphate
How much additional energy does Creatine Phosphate provide for maximal contraction? 20 additional seconds
Muscle fibers continually resynthesize ATP from the breakdown of what? Creatine Phosphate
Where does ATP bind to transfer it's energy to perform the work of pullin thin filament during contraction? Myosin head
Muscle fibers ensure an uninterrupted supply of glucose by storing it in the form of what? Glycogen
What is the catabolic process that produces the maximum amount of energy available from each glucose molicule? Aerobic (oxygen-requiring)
Where does the lactic acid return to out of the blood? the Liver and is converted back into glucose
Anaerobic respiration results in the formation of what? Lactic Acid
What gives Myoglobin it's reddish pigmentation? Iron
What muscle fibers have high levels of myoglobin Red Fibers
What muscle fibers have little myoglobin? White Fibers
What are the 3 different types of skeletal muscle fibers that can be classified according to their structural and functional characteristics? Red fibers- Slow
White fibers- Fast
Intermediate fibers
At rest excess O2 in the sarcoplasm is bound to what? Myoglobin
What type of respiration occurs when low levels of O2 are available and results in the formation of lactic acid? Anaerobic respiration
What type of respiration occurs when adequate O2 is available? Aerobic respiration
What is the functional unit that consists of a Motor neuron plus the muscle fibers to which it attaches? Motor Unit
What type of motor neuron forms that motor unit with a muscle fiber? Somatic Motor Neuron
One single contraction is called what? A twitch Contraction
What are the 3 phases of the twitch contraction? -Latent Period
-Contraction Phase
-Relaxation Phase
Each twitch contraction usually lasts how long? Less than 1/10 of a second
A series of twitch contractions or "staircase phenomenon" is called what? Treppe
What is the gradual steplike increase in the strength of contractions seen in a series of twitch contractions that occur 1 second apart? Treppe (staircase phenomenon)
What benifits do you get from warming up muscle fibers? -Calcium ions diffuse through the SR more efficiently
-More actin-myosin reactions occur
What is a smooth, sustained contraction called? Tetanus
What is caused by any combination of local failure in the steps of muscle contraction? Physiological Muscle Fatigue
What are 3 things that cause Physiological Muscle Fatigue -Lack of ATP
-Depletion of O2 or Glucose
-Build up of Lactic Acid
What is the continual, partial contraction of a muscle? Tonic Contraction
Muscles with less tone than normal are? Flaccid
Muscles with more tone than normal are? Spastic
What is the principle that skeletal muscles contract with varying degrees of strength at different times? Graded Strength Principle
When is the strongest maximal contraction possible? Only when the muscle organ has been stretched to it's optimal initial length
The maximal strength that a muscle can develope bears a direct relationship to what? Length of it's fibers
What is the response in which the body tries to maintain constancy of muscle length in response to increased load? Stretch Reflex
What are the two different type of muscle contractions? -Isotonic
-Isometric
What type of contraction is a contraction in which the tone or tension within a muscle remains the same as the length of the muscle changes? Isotonic Contraction
What does Isotonic mean? "Same Tension"
What type of contraction is a contraction in which muscle lenth remains the same while the muscle tension increases? Isometric Contraction
What are the two types of Isotonic contraction? -Concentric
-Eccentric
What type of isotonic contraction is when the muscle shortens as it contracts? Concentric
What type of isotonic contraction is when muscle lengthens while contracting? Eccentric
What are painful muscle spasms? Cramps
What are minor traumas to the body that may cause a muscle bruise? Contusion
What is an injury to skeletal muscles caused by overexertion or trauma called? Strain
What is an injury to a ligament refered as? Sprain
What are the three types of muscle tissue? -Skeletal
-Cardiac
-Smooth
What type of muscle tissues are voluntary? Skeletal
What type of muscle tissues are involuntary? -Cardiac
-Smooth
What type of muscle tissue has Striations? -Skeletal
-Cardiac
What type of muscle tissue has NO striations? Smooth
What type of muscle tissues have many nucleus? Skeletal
What type of muscle tissues are characterized by having a single nucleus? -Cardiac
-Smooth
What type of muscle tissues have narrow T Tubules that form triads with the SR? Skeletal
What type of muscle tissues have large diameter T Tubules that form diads with the SR and regulate Ca++ entry into the sarcoplasm? Cardiac
What type of muscle tissues have no T Tubules? Smooth
What type of muscle tissue has a very poorly developed sarcoplasmic reticulum? Smooth
What type of muscle tissue has a extensive Sarcoplasmic Reticulum that stores and releases Ca++? Skeletal
What type of muscle tissue has a sarcoplasmic reticulum that is less extensive than in skeletal muscle? Cardiac
What type of muscle tissue has no gap junctions? Skeletal
What type of muscle tissue has cell junctions of intercalated disks? Cardiac
What type of muscle tissue has many gap junctions? Smooth

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