Immune Alterations and Cancer
5 Written Questions
5 Matching Questions
- Hypersensitivity or allergic reaction
- Cell Mediated immunity
- Type B
- Natural Passive Immunity
- a cellular aspects,examination,study of tissue
- b baby receives antibodies from its mother through the placenta and breast milk
- c an immune response in which killer T cells attack antigen-bearing cells directly
- d Anti-A antibodies
- e an over-reaction against foreign antigens 4 types
1. rapid hypersensitivity (humoral)
2. cytotoxic/cytolytic reactions (humoral)
3. immune-complex reactions (humoral)
4. delayed hypersensitivity reactions (cellular)
5 Multiple Choice Questions
- Reactions involve IgE mast cells, chemical mediators
Labs: increased eosinophils, igE
Allergy testing--skin test, oral food challenges, avoidance therapy, environmental changes, drug therapies/patient education.....antihistamines (block h1/h2 receptors), sympathomimetic/decongestant drugs, corticosteriods, antipruritic meds (anti-itch), mast cell-stabilizing meds, leukotriene receptor antagonists
- Day old baby who is breastfeeding receives what type of Immunoglobulin?
- Cytotoxic/Cytolytic Reactions (Humoral)
Production of autoantibodies--destroy own cells/tissue.
Antibody: IgA, IgM, complement often involved
Mediators: complement lysis (cell breakdown), macrophages
Examples:Transfusion reaction, Goodpasture syndrome, ITP, Grave's disease
- production of your own antibodies as a result of vaccination or immunization
- oncologic emergency with rapid lysis of malignant cells, as the cells lyse, intracellular contents are released in blood which results in hyperkalemia, hyperphosphaemia, and hyperuricemia which puts the patient at risk for renal failure and cardiac function, early signs include n&v, anorexia, diarrhea, muscle weakness and cramping, later signs tetany, paresthesias, seizures, anuria, and cardiac arrest
5 True/False Questions
Active Passive Immunity → Artificial, serum immune globulins/antibody injections
Progression → process of moving forward, developing
(no contact inhibition)
Secondary pervention → Regular screening, altering damaged genes, Genetic screening. detect and treat.
Basophils and Eosinophils → release chemicals, tissue response
Type 1 (Hypersensitivity reaction) → Rapid Hypersensitivity (Humoral)
Can be local or systemic
Allergens inhaled, ingested, contacted or injected
Reaction comes from within.
Reaction involves IgE, mast cells, chemical mediators.