What is the cause of the increased thyroid binding globulin in pregnancy?
The increase in TBG causes decreased levels of T4 and T3 leads to what?
Slightly elevated in TSH in first trimester
What is the second phase of how the thyroid is affected in pregnancy?
HCG partially inhibits pituitary decreasing TSH
What happens in the third phase of how the thyroid is affected in pregnancy?
Deiodinase I, II, and III deiodinase thyroid hormones
(II and III in placenta)
When is fetal TRH noticed?
When does fetal T4 production start?
What does the first phase of fetal brain development depend on?
What happens in the neonate immediately after birth in regard to thyroid function?
Increase in TRH and TSH
When are the normal adult levels of TSH reached?
within 2-3 days of birth
What is the free T4 and TSH in a premature baby?
FT4 = low
TSH = normal
What happens to T4 and T3 in pregnancy?
T4 = elevated
T3 = decreased
What tests should be run on ALL women with infertility and menstrual disorders?
T4, T3, and TSH
What must type 1 DM pts have done prior to conception?
Thyroid function tests
What is associated with menorrhagia and hyperprolactinemia?
What is hyperthyroidism associated with?
How long should someone wait to conceive after having radioactive iodine studies?
How do you treat hyperthyroidism in pregnancy?
How do you treat Hypothyroidism?
What is post partum thyroiditis?
Abnormal TSH in 1st year post partum
Transient hyperthyroid 6wk - 6 months post delivery
Hypothyroid phase lasting up to 1 year after delivery
What increases post partum thyroiditis?
Type 1 DM
What are the symptoms of the first phase of post partum thyroiditis?
What are the symptoms of the second phase of post partum thyroiditis?
Decrease in Concentration
What lab values are seen in post partum thyroiditis?
Positive Antithyroid Antibodies