Antibiotics
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18 terms
Terms | Definitions |
|---|---|
 When are bactericidal drugs the first line agents used? | In seriously ill or immunocompromised patients |
| What is MIC? | Minimum inhibitory concentration, this is the lowest concentration of antibiotic that inhibits growth of tested bacteria |
| What is MBC? | Minimum Bactericidal Concentration, this is the lowest concentration of an antibiotic that kills the tested bacteria |
| What does Beta-Lactam inhibit? | Transpeptidase |
| What does Vancomycin inhibit? | Transglycosylase |
| What does Fosfomycin inhibit? | Enolpyruvate Transferase |
| What do the Aminoglycosides inhibit? | The Protein Synthesis by blocking the initiation complex. Translocation is blocked |
| What do Macrolides block? | Translocation |
| What does Chloramthenicol block? | Transpeptidation |
| What do Tetracyclines block? | Aminoacyl-tRNA binding |
| What does Quinupristin block? | Translocation |
| What does Dalfopristin do? | It changes the 50s so f. it up |
| What does Linezolid do? | It blocks the initiation complex |
| What do Sulfonamides do? | Inhibits Dihydropteroate Synthetase |
| What does Trimethoprim do? | Inhibits Dihydrogolate reductase |
| What do Quinolones do? | Inhibit Topoisomerase |
| What do Metronidazole do? | DNA damage! |
| What is Prophylactic therapy? | Prevention therapy (antimicrobial) |
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