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5 Written questions

5 Matching questions

  1. ethambutol
  2. antimicrobial agents
  3. tetracyclines
  4. semisynthetic drugs
  5. target modification
  1. a drugs partly of laboratory origin and partly of microbial origin; improve the natural product; reduce side effects
  2. b chemotherapeutic drugs used to treat infectious disease
  3. c bacteria evolve changes in drug targets like ribosomes or enzymes involved in replication
  4. d broad spectrum including chlamydias and rickettsais; destroy intestinal microbiota and cause staining of teeth; bind with calcium; put in animal feed
  5. e inhibits mycolic acid from being incorporated into the cell wall in mycobacteria; narrow spectrum; combined with rifampin and isoniazid

5 Multiple choice questions

  1. inhibits the peptide crosslinking of carbohydrates between peptidoglycan layers during wall formation
  2. used in wound tissue
  3. history of chemotherapy originated with this man; came up with concept of selective toxicity
  4. used to treat infections, diseases, and other disorders such as cancer
  5. intestinal infections; broad spectrum; ointments

5 True/False questions

  1. aminoglycosidesused against gram positive; alternative to penicillin; erythromycin blocks protein synthesis by inhibiting chain elongation (ZPAC-azithromycin)

          

  2. macrolidesused against gram positive; alternative to penicillin; erythromycin blocks protein synthesis by inhibiting chain elongation (ZPAC-azithromycin)

          

  3. Alexander Fleminginhibits the peptide crosslinking of carbohydrates between peptidoglycan layers during wall formation

          

  4. selective toxicitysays that antimicrobial agent should harm the the infectious agent but not the host

          

  5. alternate metabolic pathwayresistance to sulfonamides may develop if the bacterial enzyme changes or if the bacteria evolves an alternate metabolic pathway

          

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