C/P LAB I-Quiz Feb 27th (wkbk)

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hematology #5

Toxic neutrophils may show large:

purple granules

Which of the following cells has cytoplasmic granules that stain blue to blue-black and grey-blue cytoplasm, often with small vacuoles?

basophil

Pyknosis is a term used to describe a

small, condensed, dark, fragmented nucleus

Hemolysins

destroy RBC

Which statement is true regarding circulating leukocytes in a healthy adult cow?

always include more than one cell type

Phagocytes are a type of

WBC

Leukopenia is

a decrease in WBC

MCHC is expressed in

g/dl

Which of the following cells has a high nuclear-cytoplasmic ration, coarse, clumped, dark-staining chromatin; and a sky blue cytoplasm?

small lymphocyte

Megakaryocytes are the precursor cell to

thrombocytes

Approximately what percentage of the total erythrocyte mass is replaced every day in healthy mammals under normal circumstances?

1%

An increased amount of _____ seen on a stained periperal blood smear is a sign of RBC regeneration.

Howell-Jolly bodies

To make a smear with anemic blood,

increase the angle of the pusher slide

Which of the following RBC indices indicates cell size?

MCV

The platelets of what species tend to clump easily?

cats

RBCs with multiple, irregularly spaced projections are

acanthocytes

Reticulocytes on a modified Wright stain (eg. Diff-Quick) appear

polychromatic

What way of reporting WBC differential results is most useful?

as absolute numbers

The buffy coat in a spun hematocrit tube consists of

WBCs and platelets

What cells are phagocytic?

neutrophils and macrophages

Monocytes typically have

lobular nuclei

Which of these is not a sign of RBC regeneration?

spherocytes

A left shift refers to increased numbers of

immature neutrophils

Which vacutainer tube does not need to be inverted after collection of a blood sample?

red top

Which pair are both agranulocytes?

lymphocytes and monocytes

The least common leukocyte found on a normal bovine differential count is a(n)

basophil

Macrocytic anemia suggests

regeneration

Erythrocyte life spans vary from species to species, but the average is generally considered to be

120 days

The total WBC count of a health adult dog ranges from

6000 to 17,000/ul

Under the microscope you observe a leukocyte that you identify as an eosinophil. The eosinophil cytoplasm contains numerous rod-shaped granules. This blood sample is most likely from a healthy adult

cat

The leukocyte most commonly associated with parasite and allergic conditions is the

eosinophil

A common finding on a blood smear from an animal with autoimmune hemolytic anemia is

spherocytes

What test is usually considered of little diagnostic value?

MCH

On a complete blood count (CBC), all of the following findings could be expected in a pt with an infection, except

narrow buffy coat

An elevated hematocrit is most commonly associated with

dehydration

The hematology analyzer is not functioning properly. A good mathematical method to estimate hemoglobin is

one third the PCV

RBC fragments, resulting from shearing of the RBCs by intravascular trauma, are known as

schistocytes

Heinz bodies may be a normal finding in up to 5% of the erythrocytes in what species?

cats

The precursor cell of a thrombocyte is a

megakaryocyte

The main function of the neutrophil is

phagocytosis

The main function of the eosinphil is

allergic reaction

What information do the RBC indices yield?

the size, weight, and hemoglobin concentration of an average RBC

Where on the blood smear would you select to start your WBC differential count?

monocellular layer

In which of the following species is rouleaux formation common?

horses

Dohle bodies are found in what type of blood cell?

neutrophil

Given a PCV of 42%, which of the following is the estimated hemoglobin value?

14 g/dl

The term for RBC formation is

erythropoiesis

What is the function of the megakaryocyte?

produces thrombocytes

The refractor is used to determine

total protein

What erythrocyte index gives an indication of the average size of RBC?

MCV

When the spun hematocrit test is done, which of the following can be evaluated?

total protein, buffy coat, plasma color, and PCV

A monolayer of cells on a blood smear is best described as

cells with no overlapping or touching

"Railroad tracks" on a blood smear most often occurs when

the slide is made with inconsistent pressure

What condition could result in myoglobinuria?

prolonged recumbency

An example of capillary action is

the action of blood filiing a hematocrit tube

When using a liquid reagent-based chemistry analyzer, the higher the concentration of the substance,

the less light that will pass through the solution

A substance that has been lyophilized has been

dehydrated

Prolonged exposure of serum to the blood cells before the serum is removed from the clot can result in

increased serum phosphorus

A toxic neutrophil can be identified by all of the following characteristics, except

hypersegmentation

A Dohle body is identified with the Diff-Quik stain (modified Wright=Giemsa stain) as

a small, bluish-gray inclusion in a neutrophil cytoplasm

A blast cell is not a characteristic of

an old, degenerative cell

A target cell is also called a/an

codocyte

A crenated cell is also called a/an

echinocyte

Spherocytes may be seen on a blood smear from a dog suffering from

IMHA

Acanthocytes are

poikilocytes

A canine RBC is

a biconcave disk-shaped ceell

DIC is commonly represented by schistocytosis. The schistocytes are made when

fibrin strands cut the erythrocytes apart

Pyknosis is a term used to describe a

small, condensed, dark, fragmented nucleus

Basophilic stippling is often associated with

lead poisoning

A common finding on a stained blood smear from an animal with autoimmune hemolytic anemia is

spherocytosis

Denatured hemoglobin found in erythrocytes is

a Heinz body

What appears as a blue spheric nuclear remnant seen in some Wright-stained erythrocytes?

Howell-Jolly body

A variation in erythrocyte size is known as

anisocytosis

What is a non-nucleated, immature erythrocyte found in small numbers in the peripheral blood of dogs called?

reticulocyte

What part of the CBC is the most accurate procedure?

hematocrit

What part of the CBC cannot be done manually with adequate accuracy?

erythrocyte count

Four purple-top tubes with blood samples from four different animals are left standing the laboratory. In what sample will the RBCs settle the fastest?

horse sample

What would you expect to see on a Diff-Quik stained blood smear from an animal with regerative anemia?

polychromasia

What cell is described as a central rounded area of hemoglobin surrounded by a clear zone, with a dense ring of hemoglobin around the periphery?

target cells

What causes plasma to appear red?

hemolysis

Reticulocytes are never found in the peripheral blood of

horses

What cell is produced by megakaryocytes?

thrombocyte

What species normally has the smallest erythrocytes?

goats

What is the term used to describe the situation in which many of the erythrocytes stain varying shades of lavender?

polychromasia

Reticulocytes are reported as

%

Which of the following is a breakdown product of hemoglobin?

bilirubin

What measurement determines the average size of an erythrocyte?

mean corpuscular volume

What parasite resembles Howell-Jolly bodies?

Mycoplasma haemofelis (Haemobartonella sp.)

Basophilic stippling is seen in

erythrocyte cytoplasm

A canine erythrocyte that is smaller than normal, with no pale area in the center, is a

spherocyte

Rouleaux formation is most commonly seen on blood smears from

horses

What animal has oval erythrocytes?

normal llama

What causes dark granules called Dohle bodies in the cytoplasm of canine neutrophils?

toxemia

Which of these is an artifact?

crenation

Certain oxidant drugs can denature hemoglobin and cause production of round structures in erythrocytes called

Heinz bodies

What is the primary function of fibrinogen?

hemostasis

What nucleated erythrocyte is the first one you'll see in peripheral blood if an animal has used all of its reserves of mature erythrocytes in the bone marrow?

metarubricyte

Which of these cells is the most immature?

prorubricyte

Hemagglutination is

clumping of erythrocytes

If an erythrocyte loses part of its membrane but still remains intact, it will appear as a _____ on a stained peripheral blood smear.

spherocyte

An erythrocyte that does not contain its full amount of hemoglobin will appear as _____ on a stained peripheral blood smear.

hypochromasia

Spherocytes are _____ when viewed on a peripheral blood smear.

microcytic erythrocytes

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