BMS 508 Ch. 19

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Plasma is closest in composition to
a. CSF.
b.interstitial fluid.
c. isotonic saline solution.
d. sterile water.
e. urine.

b.interstitial fluid.

Which of the following is a function of the blood?
a. transport of nutrients and wastes
b. transport of body heat
c. transport of gases
d. defense against toxins and pathogens
e. All of the answers are correct.

e. All of the answers are correct.

The combination of plasma and formed elements is called
a. extracellular fluid.
b. serum.
c. whole blood.
d. lymph.
e. packed blood.

c. whole blood.

Whole blood for testing in a clinical laboratory is usually collected from
a. a superficial vein.
b. the heart.
c. an arteriole.
d. a capillary.
e. a superficial artery.

a. a superficial vein.

The most abundant component of plasma is
a. ions.
b. nutrients.
c. proteins.
d. water.
e. gases.

d. water.

The chief difference between plasma and interstitial fluid involves the
a. concentration of proteins.
b. concentration of water.
c. concentration of glucose.
d. concentration of nitrogen wastes.
e. concentration of electrolytes.

a. concentration of proteins.

Thyroid-binding globulin is an example of which kind of plasma protein?
a. apolipoprotein
b. transport albumin
c. metalloprotein
d. hormone-binding
e. steroid-binding

d. hormone-binding

Transferrin is an example of which kind of plasma protein?
a. metalloprotein
b. apolipoprotein
c. hormone-binding protein
d. transport albumin
e. steroid-binding protein

a. metalloprotein

Plasma proteins essential in body defense are the
a. albumins.
b. metalloproteins.
c. lipoproteins.
d. fibrinogens.
e. immunoglobulins.

e. immunoglobulins.

A plasma protein essential for blood coagulation is
a. metalloprotein D.
b. immunoglobulin A.
c. lipoprotein C.
d. albumin alpha.
e. fibrinogen.

e. fibrinogen.

All the circulating red blood cells in an adult originate in the
a. heart.
b. thymus.
c. lymph tissue.
d. red bone marrow.
e. spleen.

d. red bone marrow.

Red blood cell production is regulated by the hormone
a. renin.
b. erythropoietin.
c. angiotensin.
d. M-CSF.
e. thymosin.

b. erythropoietin.

The disease sickle cell anemia is an example of what can happen if
a. a gene for adult hemoglobin is abnormal.
b. hemolysis is prevented by a mutated gene.
c. red blood cells bind too much oxygen.
d. there is insufficient heme in the hemoglobin.
e. the diet is deficient in iron.

a. a gene for adult hemoglobin is abnormal.

An obstruction in blood flow to the kidneys would ultimately result in
a. increased erythropoiesis.
b. renal anemia.
c. pernicious anemia.
d. decreased erythropoiesis.
e. increased sensitivity to vitamin K.

a. increased erythropoiesis.

The level of erythropoietin in the blood would rise due to all of the following, except
a. when blood flow to the kidneys is disrupted.
b. at high altitudes.
c. during periods of fasting.
d. as a consequence of hemorrhage.
e. during anemia.

c. during periods of fasting.

The average life span of a red blood cell is
a. about 1 year.
b. 1 month.
c. 4 months.
d. many years.
e. 24 hours.

c. 4 months.

In adults, the only site of red blood cell production, and the primary site of white blood cell formation, is the
a. liver.
b. red bone marrow.
c. yellow bone marrow.
d. thymus.
e. spleen.

b. red bone marrow.

Each heme ring in hemoglobin encloses an atom of
a. copper.
b. calcium.
c. sodium.
d. magnesium.
e. iron.

e. iron.

Excess iron is stored in the liver and spleen as
a. hemoglobin.
b. transferrin.
c. hemosiderin.
d. ferritin.
e. hemosiderin and ferritin.

e. hemosiderin and ferritin.

A red blood cell that contains normal amounts of hemoglobin would be called
a. normocytic.
b. macrocytic.
c. hypochromic.
d. normochromic.
e. hyperchromic.

d. normochromic.

The waste product bilirubin is produced from
a. abnormal proteins found in red blood cells.
b. globin chains of hemoglobin.
c. heme molecules lacking iron.
d. iron found in hemoglobin molecules.
e. heme molecules plus iron.

c. heme molecules lacking iron.

The process of red blood cell production is called
a. erythropoiesis.
b. hematopenia.
c. erythrocytosis.
d. hemocytosis.
e. erythropenia.

a. erythropoiesis.

Which of these is not a surface antigen found on red blood cells?
a. B
b. O
c. A
d. Rh

b. O

A person's blood type is determined largely by the
a. chemical character of the hemoglobin.
b. size of the RBCs.
c. volume of the RBCs.
d. shape of the RBCs.
e. presence of specific glycoproteins on the cell membrane.

e. presence of specific glycoproteins on the cell membrane.

People with type AB blood are considered the "universal recipient" for transfusions because
a. their blood is plentiful in A and B agglutinins.
b. their blood lacks A or B agglutinins.
c. they usually have very strong immune systems.
d. their blood cells lack A and B antigens.
e. they are usually Rh negative.

b. their blood lacks A or B agglutinins.

Blood type is identified primarily by
a. the Rh blood group.
b. both the ABO and Rh blood groups.
c. the HB blood system.
d. the ABO blood group.
e. the Kahn blood group.

b. both the ABO and Rh blood groups.

Anti-D antibodies are present in the blood of
a. all individuals with type AB blood.
b. Rh negative individuals who have been exposed to the D surface antigen.
c. all Rh negative individuals.
d. all Rh positive individuals.
e. Rh positive individuals who have been exposed to the D surface antigen.

b. Rh negative individuals who have been exposed to the D surface antigen.

Antigens of the surface of red blood cells are also called ________ and antibodies in the blood plasma are also called ________.
a. serum; plasma
b. agglutinogens; agglutinins
c. erythrogens; antibiotics
d. agglutinins; agglutinogens
e. T-cells; B-cells

b. agglutinogens; agglutinins

Which of these statements about basophils is not true?
a. They release histamine.
b. They promote inflammation.
c. They are abundant.
d. They are cytoplasmic granules.

c. They are abundant.

The most numerous white blood cells in peripheral circulation are the
a. neutrophils.
b. monocytes.
c. lymphocytes.
d. eosinophils.
e. basophils.

a. neutrophils.

White blood cells that release histamine at the site of an injury are
a. monocytes.
b. lymphocytes.
c. eosinophils.
d. neutrophils.
e. basophils.

e. basophils.

White blood cells that are increased in allergic individuals are the
a. neutrophils.
b. eosinophils.
c. basophils.
d. lymphocytes.
e. monocytes.

b. eosinophils.

Which of the following is true of basophils?
a. constitute about 1 percent of WBCs
b. granules contain heparin
c. granules contain histamine
d. attract other defense cells
e. All of the answers are correct.

e. All of the answers are correct.

During a bacterial infection you would expect to see increased numbers of
a. neutrophils.
b. thrombocytes.
c. reticulocytes.
d. basophils.
e. eosinophils.

a. neutrophils.

The blood cells involved in specific immunity are the:
a. neutrophils
b. lymphocytes
c. basophils
d. erythrocytes
e. monocytes

b. lymphocytes

The function of platelets is to assist in the
a. transport of blood gases such as oxygen.
b. removal of worn out red blood cells.
c. immune response during an infection.
d. destruction of bacteria.
e. process called hemostasis.

e. process called hemostasis.

The extrinsic pathway of coagulation is initiated by the
a. activation of Factor VII exposed to collagen.
b. release of heparin from the liver.
c. sticking of platelets to damaged tissue.
d. conversion of prothrombin to thrombin.
e. release of tissue factor (Factor III) by damaged endothelium.

e. release of tissue factor (Factor III) by damaged endothelium.

The intrinsic pathway of coagulation is activated by the
a. release of heparin from the liver.
b. conversion of prothrombin to thrombin.
c. activation of Factor XII exposed to collagen.
d. sticking of platelets to damaged tissue.
e. release of tissue factor (Factor III) by damaged endothelium.

c. activation of Factor XII exposed to collagen.

The common pathway of coagulation begins with the
a. activation of a proenzyme exposed to collagen.
b. sticking of platelets to damaged tissue.
c. conversion of fibrinogen to fibrin.
d. release of tissue factor by damaged endothelium.
e. conversion of Factor X to prothrombinase.

e. conversion of Factor X to prothrombinase.

A substance that activates plasminogen might be useful to
a. cause clot dissolution to proceed faster.
b. cause clots to form faster.
c. initiate clot formation.
d. mimic heparin.
e. recruit neutrophils to an infection.

a. cause clot dissolution to proceed faster.

How would removal of calcium ions from a blood sample affect coagulation?
a. the coagulation pathway would be more sensitive to activation
b. coagulation would be prevented
c. no important effect because magnesium can substitute for calcium
d. more blood cells would be produced
e. coagulation would occur only in Rh positive individuals

b. coagulation would be prevented

A moving blood clot is called a(n)
a. platelet plug.
b. plaque.
c. procoagulant.
d. embolus.
e. thrombus.

d. embolus.

Areas in a vessel wall where large quantities of lipid accumulate are called
a. thrombi.
b. plaques.
c. clots.
d. emboli.
e. occlusions.

b. plaques.

People who suffer from hemophilia A fail to produce a functional Factor VIII; as a result
a. their coagulation times are too quick.
b. they lack a functional intrinsic pathway.
c. they lack a functional common pathway.
d. they lack a functional extrinsic pathway.
e. their coagulation times are much longer than normal.

b. they lack a functional intrinsic pathway.

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