Hormones produced by the pancreatic islets

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Alpha cells hormone

Glucagon

Alpha cells primary target

Liver, adipose tissue

Alpha cells hormonal effect

*Mobilizes lipid reserves
*Promotes glucose synthesis and glycogen breakdown in liver
*elevates blood glucose concentrations

Alpha cells regulatory control

*Stimulated by low blood glucose concentrations
* Inhibited by GH-IH from delta cells

Beta cells hormone

Insulin

Beta cells Primary target

most cells

Beta cells hormonal effects

*facilitates uptake of glucose by target cells
*stimulates formation and storage of lipids and glycogen

Beta cells regulatory control

*Stimulated by high blood glucose concentrations, parasympathetic stimulation, and the
* high levels of some amino acids
* Inhibited by GH-IH from delta cells and by sympathetic activation

Delta cells hormone

GH-IH

Delta cells primary targets

other islet cells
digestive epithelium

Delta cells hormonal effect

Inhibits insulin and glucagon secretion; slows rates of nutrient absorption and enzyme secretion along digestive tract

Delta cells regulatory control

Stimulated by protein rich meal

F cells hormone

pancreatic poly peptide PP

F cells hormonal effect

Inhibits galbladder contraction;
*regulates production of pancreatic enzymes
*Influences rate of nutrient absorption by digestive tract

F cells Regulatory control

Stimulated by protein rich meal and by para sympathetic stimulation

F cells primary target

digestive organs

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