First to isolate DNA
Discovered transformation and transfer of genetic material through bacteria and rats
Proved DNA was not a protein
Hershey and Chase
Made DNA accepted as a genetic material. Showed DNA enters bacterium through virus
Showed structure of DNA is phosphate-sugar-Nitrogenous base
DNA is specific to species. Nitrogenous base proportions are constant to a species, but change between species. Adenine and Guanine are present in same quantities and Thymine and cytosine are present in same quantities.
Crystallography- used x-ray crystallography to record 3D model of DNA. Tells atomic structure through 3D model.
Watson and Crick
Created first 3D correct Double Helix model with antiparallel strands of DNA. Also stated A bonds with T and G bonds with C.