Sets (113)
Classes (0)
Cancer Therapy definitions
| # | Definition | Sets |
|---|---|---|
| 1 | radiation sickness, immunosupression, fibrosis, burns, delayed wounds healing, edema, hair loss, cns effects. | 7 sets |
| 2 | gi symtpoms htn steroid-induced diabetes and myopathy weight loss hot flashes and sweating altered mental status impotence | 7 sets |
| 3 | directed at confining and then killing malignant cells | 6 sets |
| 4 | complex, directional | 6 sets |
| 5 | go intermittent (does not work in g0 phase); combination therapy | 2 sets |
| 6 | surgery for solid tumors that are accessible; chemotherapy for cells that remain after surgery or for diffuse tumors; radiotherapy after surgery or chemotherapy | 2 sets |
| 7 | usually a combination of these surgery radiation chemotherapy immunotherapy gene therapy stem cell transplant | 2 sets |
| 8 | directed at confining and then killing malignant cells. | 2 sets |
| 9 | -great because is not systemic (will not give the other parts of body the side effects) -targeted towards tumors themselves, attach themselves onto the receptors on the blood vessels and make necrotic. so tumor can't get blood supply and die. -two approved drugs: sunitnib (sutent) and sorafenib (nexavar); these are antiangiogenic drugs (starve the tumor by disrupting its blood supply) -another approved drug, temsirolimus (torisol) targets a different protein that controls tumor growth and blood vessel formation -clinical trials are testing combinations of these and other new drugs. | 1 set |
| 10 | target the cancer stem cells, leading to tumor regression | 1 set |
| 11 | genedicine: first gene therapy product to be licensed, approved by state food and drug administration, china 2003. adenoviral vector expressing p53, a tumor suppressor gene, injected into tumors. developed by sibiono genetech, chinese company. effective for many solid tumor cancers | 1 set |
| 12 | with mutations, tumors can overgrow using glucose and amino acids from the body. | 1 set |
| 13 | receptor activation or blockage, interferes with cellular growth and signaling | 1 set |
| 14 | resistant cells! | 1 set |
| 15 | 1. corrective gene therapy 2. cytoreductive: reduce growth/create apoptosis, stop angiogenesis 3. immunostimulatory mechanisms | 1 set |
| 16 | radiation therapy and chemotherapy targets actively dividing cells may compromise immune system | 1 set |
| 17 | radiation is used to kill the tumour cells. | 1 set |
| 18 | -antidepressants and anticonvulsants -transdermal lidocaine -corticosteroids -benzodiazepines (muscle spasms) -nsaids | 1 set |
| 19 | targeting tumor microenvironments | 1 set |
| 20 | differentiate tumor cells, no specific examples, controversial | 1 set |
| 21 | increase calorie increase protein | 1 set |
| 22 | reintroduction of tumour suppressor genes activation of immune system apoptotic genes increase suceptibiltiy to chemotherapy block angiogenisis | 1 set |
| 23 | gene therapy - place dna template into cell,transcribe mrna and express the protein as a costimulatory protein; then induce cells to synthesize the protein on mass scale dna를 세포에 넣음, mrna를 만들고 costimulatory단백질을 표현하고 셀이 mass scale프로틴을 생성하게 한다. | 1 set |
| 24 | replacement of defective gene with normal copy of gene. permanent incorporation and expression is extraordinarily difficult! | 1 set |
| 25 | nursing interventions: monitor labs-cbc, rbc, hgb, platelets, wbc's and liver function test. assess for signs of complications and interactions with food and medications. give antiemetics for nausea and vomiting | 1 set |
| 26 | 1950- screening plants for cures | 1 set |
| 27 | cancers due to activation of lmo2 protooncogene. | 1 set |
| 28 | cure is the major objective prevent further metastasis relieve symptoms maintain a high quality of life for as long as possible | 1 set |
| 29 | -radiation -reach all body cells via blood stream -# of cells replicating to # of cells resting -alkylating agents, antimetabolite, antitumor antibiotics, natural products,hormonal agents -slows resistance and kills tumor more thoroughly | 1 set |
| 30 | -specifically targets a protein that cancer cell is using to survive -need to know if patient's tumour carries mutant protein (tumour genotyping) | 1 set |
| 31 | radiation and chemotherapy | 1 set |
| 32 | what is post-transplant lymphoproliferative disease | 1 set |
| 33 | early detection best prognosis for cure. mainstayv | 1 set |
| 34 | less chance of resistance if treat with two drugs at once | 1 set |
| 35 | surgery, radiation, chemotherapy agents, immunotherapy | 1 set |
| 36 | 1.surgery 2. radiation 3. chemotherapy agents 4.immunotherapy(surgery) | 1 set |
| 37 | tyrosine kinase receptors: tyrosine kinase receptors are usually good targets for ___________ ________ | 1 set |
| 38 | early detection best prognosis for cure mainstays of therapy -surgery -radiation therapy -chemotherapy -drug therapy emerging therapies -immunotherapy -targeted molecular therapies -stem cell transplantation | 1 set |
| 39 | -chemotherapy: cytotoxic that target rapidly dividing cells. makes you unable to do mitosis. -radiotherapy: high energy radiation targeted to tumor site. - makes that area unable to make new cells. no new gi tract. bad skin. loss of hair. - attacks cancer but also destroys stem cells in bone marrow (no new red or white blood cells -> anemic and bad immune system. - hard to deliver cancer suppressors to the brain. can't use chemotherapy. use high radiation therapy which causes brain swelling. | 1 set |
| 40 | surgery, radiation, drug, immunotherapy, gene and molecular therapy, stem cell | 1 set |
| 41 | • il-2 (lak and ctl activation - tils) • tnf-α (anti-tumor at low doses) • inf-α (anti-tumor proliferation, increases nk cells activity, increase class i mhc) | 1 set |
| 42 | • lak cell therapy • til cell therapy | 1 set |
| 43 | is rendered almost incomprehensibly complicated by the sheer number of genetic mutations that must be corrected, and also by the complex relationship between the mutation and later promotors of disease | 1 set |
| 44 | certain cancers involving the breast, uterus, and prostate gland appear to be dependent on the presence of sex hormones. in some cases, the use of sex hormones seems to decrease tumor growth, whereas in others the removal of the ovaries or testes can produce beneficial results. megestrol is specifically used in the treatment of breast cancer. | 1 set |
| 45 | confining and killing malignant cells | 1 set |
| 46 | surgery, radiation, drugs | 1 set |
| 47 | cancer results from multiple gene mutations. it may be possible to deliver function genes to tumors to reverse the cancer phenotype. such therapy would require the reverse of the defect in a large number of tumor cells to cure. temporary expression of the gene may be sufficient to kill the tumor, however. | 1 set |
| 48 | • ivgg: iv gammaglobulin, immunedeficiencies • herceptin • herceptin (a.k.a. trastuzumab) targets the her-2/neu growth factor receptor (overexpressed on 25% of breast cancers) • blocks receptor/ligand interaction → ↓ expression of her-2/neu • over-expression of her-2/neu correlates with a poorer prognosis • immunoconjugates: antibodies coupled to toxic substances • bi-specific antibodies: engineered to recognize tumor antigens and immune system cells | 1 set |