- 1 week: How long it takes for haptoglobin levels to return to normal after hemolysis depletion.
- 3.5-5.0 g/dL: Reference range for Albumin.
- 3g: During intravascular hemolysis haptoglobin can take on up to _________ of hemoglobin.
- 6-8 g/dL: Reference range for total protein.
- Albumin: This protein is the first protein lost through the glomerulus.
- Albumin: This protein goes up in dehydration.
- Albumin: This protein goes down in inflammation, nephrotic syndrome, GI loss, and malnutrition.
- Alpha helix or Beta pleated sheets: The secondary structure of proteins consists of...
- Amino acid sequence: The primary structure of a protein is made up of...
- Amino aciduria: This condition has primary and secondary causes that include inherited genetic defect and renal tubular dysfunction.
- Ammonium sulfate: This compound aids in the "salting out" of soluble serum proteins.
- Amniotic fluid and mother's serum: Analyzed to find alpha1 fetoprotein.
- CRP: This protein is the first indication of inflammation in the body.
- Decrease: Intravascular hemolysis, transfusion reactions and malaria cause a/n ______________ in haptoglobin.
- Diet without phenylalanine (including treatment with amino acid-tyrosine to make up for inability to produce it from phenylalanine): Treatment for phenylketonuria.
- Globular proteins: These proteins are small spheres with little to no water inside. They have hydrophobic amino acids in the inside and hydrophilic R groups on the outside.
- Increase: Burns and nephrotic syndrome cause a/n ________________ in haptoglobin.
- Inherited genetic defect (autosomal recessive): >70% of amino acidurias are caused by this and are referred to as primary causes.
- Liver: Most serum proteins are produced here.
- Liver damage (causing over flow) and renal tubular dysfunction: The two secondary causes for amino aciduria.
- Metabolite accumulation: A primary cause for amino aciduria can lead to...
- pH, temperature: Tight range of ___________ and ____________ stability are needed or else the globular proteins will denature.
- Phenylketonuria: This disease is marked by a phenylalanine hydroxylase deficiency leading to the accumulation of phenylalanine and toxic products.
- Polypeptides that fold in on themselves: The tertiary structure of proteins consist of...
- Prealbumin: This can often be a more sensitive indicator of protein malnutrition or liver dysfunction.
- Prealbumin: This protein's level goes down when there is inflammation or malignancy.
- Retinol-Binding Protein: This protein's levels go up in liver dysfunction, protein malnutrition, and chronic renal disease.
- Retinol-binding protein (RBP) and Transthyretin (TTR): Prealbumin consists of...
- RIA: This test is used to analyze alpha1 fetoprotein.
- Severe mental retardation: This is a consequence of not treating a baby with phenylketonuria.
- Sialic acid: The part of the RBC membrane that gives it a negative charge.
- Spina bifida: Alpha1-Fetoprotein is used to study neural tube defects that are indicative of...
- Subunit aggregation (with or without prosthetic groups): The quaternary structure of proteins consists of...
- Zinc deficiency: This is characterized by a low RBP and low total vitamin A.