 | Term | Definition |
| |
Angiotensin receptor blockers (ARBs) |
Antagonists of cell surface receptors; HTN, heart failure, chronic renal insufficiency |
| |
Beta-adrenoceptor blockers |
Antagonists of cell surface receptors; angina, myocardial infarction, heart failure, high blood pressure, performance anxiety |
| |
Mineralcorticoid receptor antagonists |
Antagonists of nuclear receptors; Edema due to liver cirrhosis, heart failure |
| |
Estrogen receptor antagonists |
Antagonists of nuclear receptors; Prevention/treatment – breast cancer |
| |
Cyclooxygenase inhibitors |
Enzyme inhibitors; Pain relief, esp. arthritis |
| |
HMG-CoA reductase inhibitors |
Enzyme inhibitors; hypercholesterolemia |
| |
Angiotensin converting enzyme (ACE) inhibitors |
Enzyme inhibitors; HTN, heart failure, chronic renal insufficiency |
| |
Pancreatic lipase inhibitors |
Enzyme inhibitors, weight reduction |
| |
Calcium channel blockers (CCB) |
Ion channel blockers; angina, HTN |
| |
Sodium channel blockers |
ion channel blockers; cardiac arrhythmias |
| |
Selective serotonin reuptake inhibitors (SSRI) |
transport inhibitors; depression |
| |
inhibitors of Na-2Cl-K symporter (loop diuretics) in renal epithelial cells |
transport inhibitors; edema |
| |
tyrosine kinase inhibitors |
signal transduction inhibitors; chronic myelocytic leukemia |
| |
type 5 phosphodiesterase inhibitors |
signal transduction inhibitors; erectile dysfunction |
| |
alpha1-adrenoceptor agonists |
agonists of cell surface receptors; nasal congestion |
| |
opioid receptor agonists |
agonists of cell surface receptors; analgesia |
| |
estrogen receptor agonists |
agonists of nuclear receptors; hormone replace therapy in post-menopausal women |
| |
glucocorticoid receptor agonists |
agonists of nuclear receptors; inflammation |
| |
PPAR (peroxisome proliferator-activated receptor) agonists |
agonists of nuclear receptors; dyslipidemias |
| |
activators of guanylyl cyclase |
enzyme activators; angina |
| |
reactivators of cholinesterase |
enzyme activators; poisoning with nerve gas or organophosphate pesticide |
| |
potassium channel openers |
ion channel openers; hair regrowth |
| |
GABA-A chloride channel openers |
ion channel openers; anxiety |
| |
vinca alkaloids |
structural protein disrupters; cancer |
| |
colchicine |
structural protein disrupters; gout |
| |
thrombolytic therapy |
enzymes; acute MI |
| |
DNA alkylating agents |
covalently link to macromolecules; cancer |
| |
antacids |
react chemically with small molecules; neutralize gastric acid |
| |
bile-acid sequestrants |
bind free molecules or atoms; hypercholesterolemia |
| |
chelating agents |
bind free molecules or atoms; heavy metal poisoning |
| |
vitamins, minerals, lipids, carbohydrates, amino acids |
nutrients; prevents death |
| |
bulk laxatives |
exert actions due to physical properties; constipation |
| |
osmotic diuretics |
exert actions due to physical properties; edema |
| |
antisense deoxyoligonucleotides |
work via an antisense action; CMV retinitis in AIDS patients |
| |
vaccines |
antigens |
| |
inhalation anesthetics |
unknown mechanisms of action; general anesthesia |
| |
proteins that bind TNF-alpha |
bind free molecules or atoms; rheumatoid arthritis |
| Add or remove terms from this set |
