| Term | Definition |
|
Griffith |
discovers that a factor in heat-killed, disease-causing bacteria into ones that can cause disease |
|
Avery |
determines that genes are composed of DNA |
|
Hershey |
concluded with Chase that the genetic material of the bacteriophage was DNA |
|
Chase |
conculded with Hershey that the genetic material of the bacteriophage was DNA |
|
Watson & Crick |
developed the double helix model of the structure of DNA |
|
Chargoff |
showed that the percentage of guanine and cytosine are almost equal; the same is true for adenine and thymine |
|
Nucleotide Structure |
has 3 parts= a phosphate group, deoxyribose group, and a nitrogenous base; the four different bases in DNA are adenine, thymine, guanine and cytosine |
|
DNA Structure |
DNA is a double helix in which 2 strands are wound around eachother; each strand is made up of a chain of nucleotides, the 2 strands are held together by the hydrogen bonds between adenine and thymine and between guanine and cytosine |
|
DNA Replication |
during DNA replication, the DNA molecule produces 2 new complementary strands. each strand of the double helix of DNA serves as a template for the new strand |
|
DNA Polymerase |
the principal enzyme involved in DNA replication; it joins individual nucleotides to produce a DNA molecule |
|
Protein Synthesis |
three main types of RNA: mRNA, rRNA, & tRNA; ribosomal RNA is combined with proteins to form ribosomes |
|
Transcription |
RNA polymerase binds to DNA and seperates the DNA strands, RNA polymerase then uses one strand of DNA as a template from which nucleotides are assembled into a strand of RNA |
|
Translation |
the cell uses the info form the mRNA to produce proteins |
|
Histones |
Tthe DNA that is tightly coiled around protiens |
|
Chromatin |
eukaryotic chromosomes contain both DNA and protein tightly packed together to form chromatin |
|
mRNA |
RNA molecules that carry out copies of instruction for assembling amino acids into proteins |
|
rRNA |
ribosomes are made up of several dozen proteins as well as a form of RNA |
|
tRNA |
transfers each amino acid to the ribosome as it is specified by coded messages in mRNA |
|
Codon |
3 nucleotide sequence on mRNA that codes for a single amino acid |
|
Amino Acid |
compound with an amino group on one end and a carboxyl group on the other end |
|
Exons |
expressed sequence of DNA; codes for a protein |
|
Introns |
sequence of DNA that is not involved in coding for a protein |
|
Mutations |
Point Mutations=involving changes in one or a few nucleotides; occur at a single point in DNA sequence: frameshift mutations=shifts the "reading" frame of the genetic message by inserting or deleting a nucleotide |