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| amantadine definitions | |||
|---|---|---|---|
| # | Definition | Sets | |
| 1 | symmetrel | 21 sets | |
| 2 | parkinson | 3 sets | |
| 3 | blocks viral penetration/uncoating; prophylaxis and treatment of influenza a rubella; can treat parkinson's disease (causes the release of dopamine from intact nerve terminals) | 2 sets | |
| 4 | parkinson's, inhibit nmda glutamate receptor at pcp/ketamine site | 2 sets | |
| 5 | parkinson's treatments, dopamine releasing agent | 2 sets | |
| 6 | pd agent; enhances da synth/release; weak -glu/nmda-r -> neuroprotective; tx: mod decr of rigidity, bradykin; ade: restlessness, agitation, confusion, hallucination, orthostat hypoten | 1 set | |
| 7 | pd agent; enhances da synth/release; weak -glu/nmda-r -> neuroprotective; tx: mod decr of rigidity, bradykin; ade: restlessness, agitation, confusion, hallucination, orthostat hypotension, ankle edema. help with l-dopa induced dyskin, unlike ach-, drug may help with rigidity and bradykinesia. dose: 100 mg w/bkfast, after 1 wk add 100 mg qd in afternoon. decrease dose if cl is less than 80, tachyphylaxis in 1-2 mo. also may cz dystonias | 1 set | |
| 8 | parkinson's treatment; dopamine releasing agent, , symmetrel | 1 set | |
| 9 | aka symmetrel; antiviral; inhibits viral entry into cell, limited activity only to rna viruses (influenza a); used for influenza a and *parkinson's | 1 set | |
| 10 | symmetrel ®, dopamine antagonist s/e: lightheadedness, dizziness, insomnia, nausea * cleared by kidneys, potentially nephrotoxic = monitor bun | 1 set | |
| 11 | can increase dopamine release for parkinson, antiviral for influenza a, and rubella. (ataxia tox) | 1 set | |
| 12 | mechanism of action: 1-enhances the release of dopamine 2-inhibition of da reuptake 3-antimuscarinic 4-glutamate receptor blocking activity especially at nmda (nmethyl- d-aspartate) receptors clinical applications less effective than levodopa effective only for few weeks (rapid tolerance) side effects confusion, hallucinations, orthostatic hypotension, urinary retention, constipation, dry mouth | 1 set | |
| 13 | tablet & liquid | 1 set | |
| 14 | symmetral | 1 set | |
| 15 | nmda receptor -, promote da release, blocks ach. use in early pd for tremor and maybe bradykinesia. good for l-dopa induced dyskinesias (choreoform), tachyphylaxis in 1-2 months, adr: dystonia (painful muscle contraction). start with 100 mg brk, after 1 wk add 100 mg daily in early afternoon. decrease dose as cr cl <80 ml/min. | 1 set | |
| 16 | antiviral for influenzavirus that prevents viruses from entering cell, inhibit viral endocytosis | 1 set | |
| 17 | clinical use: osteltamavir-resistant influenza | 1 set | |
| 18 | interferes with virul uncoating;used in treatment of influenza a(including swine flu) | 1 set | |
| 19 | pk: renal elimination; 90% excreted unchanged in the urine | 1 set | |
| 20 | ae: n/v, cns toxicity, insomnia, altered concentration, seizures, suicidal ideations* | 1 set | |
| 21 | oral / inhibits influenza a virus penetration or uncoating. for prophylaxis of influenza a virus. | 1 set | |
| 22 | antiviral compound sometimes used to treat influenza type a infections. | 1 set | |
| 23 | stimulates release of dopamine? | 1 set | |
| 24 | an antiviral agent that prevents penetration by influenza a viruses | 1 set | |
| 25 | drug that fights influenza a by interfering with transcription vdna-->mrna | 1 set | |
| 26 | m2 ch blocker (no acid for uncoating) & øhemagglutinin. | 1 set | |
| 27 | symmetrel; ion channel blocker (prevents release of viral rna into host cell), used in influenza a - also used in pd | 1 set | |
| 28 | used for influenza a. prevents viral penetration and uncoating | 1 set | |
| 29 | non-competitive inhibitors of glutamate nmda receptors by binding to pcp/ketamine site | 1 set | |
| 30 | ae. nausea,convulsion, vomiting, anorexia | 1 set | |
| 31 | ataxia, livedo reticularis | 1 set | |
| 32 | parkinson's treatments, dopamine releasing agent | 1 set | |
| 33 | treat parkinsonism | 1 set | |
| 34 | nucleoside analogue vs. influenza a; prophylactic; interferes w/ transcription vdna->mrna | 1 set | |
| 35 | blocks uncoating, stimulates d2 release, treats influenza a (parkinsons dz) side effects: erebellar sx | 1 set | |
| 36 | increase presynaptic release of da and inhibit reuptake | 1 set | |
| 37 | parkinson's treatment; dopamine releasing agent | 1 set | |
| 38 | prophylaxis against influenza a and rubella | 1 set | |
| 39 | what antiviral agent is used in the treatment of drug-induced parkinson's disease? | 1 set | |
| 40 | what antiviral agent blocks the attachment and penetration of influenza a virus? | 1 set | |