Quizlet
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| infliximab definitions | |||
|---|---|---|---|
| # | Definition | Sets | |
| 1 | remicade | 5 sets | |
| 2 | immunomodulators, monoclonal antibodies used to treat inflammatory disorders, anti tnfα for crohns, uc, ra, ankylosing spondylitis | 3 sets | |
| 3 | immunomodulator | 2 sets | |
| 4 | antirheumatic, anticytokine; chimeric monoclonal ab; binds/neut soluble & transmem forms of tnfa -> decr stim of il1,6, decr wbc migration into synovial fluid; synergism when given with mtx; ade: ha, inf rxn, rash, malignancy; ci: infection/sepsis, murine hypersensitivity, chf | 2 sets | |
| 5 | treats rheumatoid arthritis | 1 set | |
| 6 | anti-tnf antibody, use for ra but watch out for latent tb! | 1 set | |
| 7 | an agent that is used to treat rheumatoid arthritis is | 1 set | |
| 8 | tnf-a, ra and chrons | 1 set | |
| 9 | ibd, immunosupress; monoclonal ab against tnfa; | 1 set | |
| 10 | for crohn's disease | 1 set | |
| 11 | binds with high affinity to soluble and transmembrane forms of tnf-a, inhibit function | 1 set | |
| 12 | immuno supressantmonoclonal antibody against tnf-alphasingle i.v. effective at inducing remission in crohn'sside effects: nausea, serum sickness like reactions, infections, unclear | 1 set | |
| 13 | crhon's disease, ulcerative colitis, ra, psoriatic arthritis, ankylosing spondylitis | 1 set | |
| 14 | remicade- ( biological response modifier) arthritic psoriasis | 1 set | |
| 15 | igg1 monoclonal antibody; binds to soluble and bound tnf-alpha | 1 set | |
| 16 | monoclonal antibody, binds to cytokine tumour necrosis factor alpha (tnf-a). tnf-a levels elevated in many inflammatory disorders eg arthritis. infliximab binds and neutralises tnf-a lowering its conc. chimeric antibody (contains protein sequences from both human and mouse antibodies)- recombining mouse dna sequences that code for variable regions of the antibody with human dna sequences that code for constant regions | 1 set | |
| 17 | monoclonal antibody against tnfa (immunosuppressant). generally well tolerated. | 1 set | |
| 18 | gi: monoclonal antibody to tnf can also be used in these inflammatory bowel disorders; also sued in rheumatoid arthritis | 1 set | |
| 19 | ab binds to tnfa and prevents the cytokine from binding its receptor. immunosuppressant. may also be used in crohn's disease. | 1 set | |
| 20 | crohn's dz & fistulas- antibody against tnf alpha, se: allergies | 1 set | |
| 21 | binds tnf-a preventing it from binding its receptor | 1 set | |
| 22 | remicade.serious infections including sepsis and disseminated tuberculosis | 1 set | |
| 23 | to treat autoimmune disorders, blocks the action of tnfα by binding to it and preventing it from signaling the receptors for tnfα on the surface of cells, treatment of psoriasis,crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis | 1 set | |
| 24 | crohn's dz, ra, ankolysing spondylitis. tnfalpha antibody | 1 set | |
| 25 | remicade---rheumatoid arthritis, crohn's disease | 1 set | |
| 26 | what is the name of the monoclonal antibody used in the treatment of crohn disease and rheumatoid arthritis? | 1 set | |
| 27 | inflammation, disease-modifying anti-rheumatic drugs (dmards) tnf-alpha blockers | 1 set | |
| 28 | binds and inhibits tnf-alpha | 1 set | |
| 29 | monoclonal antibody to tnf; used to treat crohn's disease and rheumatoid arthritis; can cause respiratory infection, fever, hypotension | 1 set | |
| 30 | anti-tnf antibody; treats crohn's disease, rheumatoid arthritis, ankylosing spondylitis; can predispose to infections, reactivate latent tb | 1 set | |
| 31 | remicade/tumor necrosis factor blocking agent | 1 set | |
| 32 | immunomodulators; monoclonal antibodies; monoclonal antibody against tnfalpha used to treat crohns, uc, ra, ankylosing spondylitis | 1 set | |
| 33 | binds tnfα therefore inhibiting inflammation | 1 set | |
| 34 | murine/human chimeric monoclonal antibody, binds tnf-alpha, causes apoptosis of immune cells | 1 set | |
| 35 | remicade: monoclonal antibody used to treat a variety of inflammatory conditions | 1 set | |
| 36 | remicade-monoclonal antibody used to treat a variety of inflammatory conditions (e.g. rheumatoid arthritis, ulcerative colitis, crohn's) | 1 set | |
| 37 | dmards: chimeric monoclonal anti tnfalpha natibody, binds to human tnfa, be careful human antichimeric antibodies (haca) | 1 set | |