Omalizumab flashcard sets

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omalizumab definitions
# Definition Sets
1xolair2 sets
2antiasthma; ab against ige -> prev ige from binding mast cells, basophils -> prev degran/release if inflamm med, decr fcer1; requires >90% reductn of ige for eff; ade: inj rxn, ha, itch2 sets
3(b.n.); xolair1 set
4immunomodulator; rna derived antibody1 set
5antibody against fc region of ige1 set
6human monoclonal antibody against human ige, which is found on the surface of mast cells and basophils; se: throat irritation, cough1 set
7antagonist to mast cell binding with ige1 set
8toxicity: injection site, anaphylactic reactions, increased risk of heart disorders1 set
9ige, asthma1 set
10inds cre3 region of ige, lowers free serum ige, reduces amt of ige bound to mast cells, binding of cre3 by anti-ige keeps ige from biding feri, reduces number of fceri1 set
11ige antibody-based drug1 set
12sc injection; approved for asthma only!1 set
13asthma, anti-inflammatory agents, anti-ige therapy1 set
14control med for patients with severe asthma that has an allergic component, usually given when other drugs fail to control the asthma1 set
15anti-ige ab that reduces release of mediators from mast cells and basos; subq every 2-4 weeks; for asthma and rhinitis1 set
16a monoclonal antibody that binds ige; not a first line treatment1 set
17allergy/ asthma suppression by binding ige thus preventing it from binding to fc receptors on mast cells decreasing likeliness of hyperreactive mast cells1 set
18anti- ige agent1 set
19asthma; anti-inflammatory agents; anti-ige therapy1 set