Selegiline flashcard sets

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selegiline definitions
# Definition Sets
1mao-b inhibitor5 sets
2eldepryl4 sets
3inhibit maob, increase da & 5ht4 sets
4elderpryl3 sets
5antidepressants, maoi type b2 sets
6parkinson's treatments, moa b inhibitors, does not cause hypertensive crisis; deprenyl2 sets
7mechanism: selective mao type b inhibitor which prevents dopamine breakdown; clinical: parkinsons adjunctive therapy; se: enhance adverse effects of l dopa1 set
8a monoamine oxidase type b (mao-b) inhibitor that slows the breakdown of dopamine in the brain and may also block its reuptake at the synapse1 set
9monoamine oxiadase inhibitor. blocks the reuptake of dopamine and is used to treat cognative dysfunction in dogs.1 set
10mao inhib1 set
11inhibits mao-b; used for parkinson's1 set
12transdermal skin patch, slow continuous absorption. drug interactions not observed yet. very effective, onset a few days, no sexual dysfunction. inhibits mao-a in brain much more than in gi tract absorption bypassed)1 set
13(eldepryl)1 set
14mao-i; relatively selective for mao-b (da), used in pd and major depression1 set
15selective mao-b inhibitor (minor side effects - insomnia, headache)1 set
16mao-b inhibitor (selective, treats parkinson's)1 set
17adrenergic: selective and irreversible mao-b inhibitor, adjuct in parkinson's, less likely to increase bp1 set
18breaks down maob1 set
19selective mao-b inhibitor (parkinson's)1 set
20mao-b inhibitor which inhibits dopamine breakdown and can reduce "wearing off" effect of levodopa1 set
21aka deprenyl; indirect dopaminergic drug- inhibits mao-b, which preferentially metabolizes dopamine (less effect on 5ht and ne) -> increases da concentration1 set
22what maoi does not cause a hypertensive crisis?1 set
23emsam1 set
24what is the monoamine oxidase b (maob) inhibitor?1 set
25what is the drug of choice for early parkinson's disease?1 set
26inhibits mao-b1 set
27inhibits degradation of dopamine in cns, used with levodopa for parkinson's1 set
28eldepryl-severe hypotension and psychomotor agitation1 set
29early stage parkinson's disease and senile dementia1 set
30antidepressant; maoi (type b)1 set
31mao-b inhibitor, decreases da metabolism in cns and prolongs action; use as adjunct to levodopa therapy1 set
32selectively inhibits mao-b thereby increases the availability of dopamine; used as an adjunctive agent to l-dopa in treatment of parkinson's disease1 set
33parkinsons. selective mao-b inhibitor prevents dopamine breakdown1 set
34mao type b inhibitor for parkinson's1 set
35may enhance adverse effects of l-dopa1 set
36irreversible mao-b inhibitor, amphetamine and methamphetamine are possible metabolites1 set