Sildenafil flashcard sets

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sildenafil definitions
# Definition Sets
1viagra20 sets
2erectile dysfunction5 sets
3gu drug; tx: ed; inhib pde5 -> incr cgmp -> sm m relax -> bl flow to cavernosum; ade: potentiates action of nitrates, color vision changes, naion3 sets
425, 50, 1002 sets
5phosphodiesterase type 5 inhibitor responsible for degrading cgmp which is a smooth muscle relaxant, requires functional innervation, adequate blood flow and sexual stimulation to work, also useful in pulmoary arterial hypertension, increasing exercise tolerance and pulmonary pressure. adverse effects include potentiating action of nitrates on blood pressure and color vision changes due to phosphodiesterase type 5 in the eye and nonarteritic ischemic optic neuropathy1 set
625 50 1001 set
7erectile dysfunction, viagra1 set
8example of pde5 inhibitor1 set
925, 50, 100 (os)1 set
10os1 set
1125, 50, 100 mg1 set
12pde5/pde6 inhibitor1 set
13oral solid1 set
14blocks pde 5 which switches cgmp to gmp this increase cgmp which leads to dephoshorylation fo the mlck1 set
15viagra/phosphodiesterase type 5 enzyme inhibitor1 set
16viagra, revatio1 set
17phosphodiesterase inhibitors; pd e5 inhibitor1 set
18autocoids; prostaglandins; for erectile dysfunction; absolutely contraindicated in patients taking nitrate drugs1 set
19increase no by cgmp = signal transducton1 set
20viagra; phosphodiesterase-5 enzyme inhibitor; ed1 set
21autocoids; prostaglandins; trade name viagra1 set
22x cgmp +no x sig transduction1 set
23revatio1 set
24this pde5 inhibitor can cause profound hypotension if taken with a nitrate1 set
25substrate1 set