Sumatriptan flashcard sets

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sumatriptan definitions
# Definition Sets
1imitrex31 sets
2migraines, activate 5-ht1b presynaptic receptors, activate 5-ht1d postsynaptic receptors2 sets
3autocoids, biogenic amines, triptans, imirex2 sets
4migraine headache tx1 set
5causes vasoconstriction (use for acute migraines)1 set
6imitrex (vasoconstrictor)1 set
71d agonist selective t; 1st line therapy for acute migraine attack. ci; asthma patients. inhibits release of vasoactive peptides. short acting. expensive1 set
8mechanism: 5ht agonist which causes vasoconstriction, inhibition of trigeminal nerve activation and vasoactive peptide release, short t1/2; clinical: acute migraine, cluster headaches; se: conorary vasospasm, mild tingling (contraindicated in patients with prinzmetals angina or cad)1 set
9migraine tx; selective +5ht-1b/1d; pre + post synap, inhib migraine generation + decr depol of trigeminal nerve and vap release1 set
10anti-migraine1 set
1125, 50, 100 mg as needed1 set
125-ht agonist1 set
13selective 5-ht 1b/1d agonist also 5-ht 1f1 set
14imitrex oral/serotonin 5-ht receptor agonist1 set
15what is the 1st line treatment of migrain headaches in non-pregnant individuals?1 set
16causes contraction of vessels in carotid circulation w/o affecting major organs' blood supply; blocks trigeminal neuropeptide release; 6/month or 2/week1 set
175-ht1d agonists. coronary vasospasm (contraindicated for cad or angina)1 set
18acute migraine, cluster headache. 5ht1d agoinist causing vasoconstrction (se=coroanary vasospasm contraindicated w/cad anginia)1 set
19used for acute migraine and cluster headaches1 set
20causes vasoconstriction of cerebral vasculature1 set
21binds the serotonin 1d receptor1 set
225-ht(1d) agonist, causing vasoconstriction; used to treat acute migraine, cluster headache attacks; toxicity includes coronary vasospasm, mild tingling, hypertensive emergencies1 set
23sumatriptan succinate1 set
24a relatively specific 5-ht-1d receptor agonist available in tablet form, subq injection, nasal spray; more effective than analgesics, ergot derivatives; also effective against n&v1 set
25autocoids; biogenic amines; triptans; for migraine use; 5-ht1 agonist1 set
26this serotonin agonist is given as a treatment for an acute migraine headache1 set
27imitrex oral1 set
28initrex(r)1 set
29higher recurrence of migraines possibly b/c of short t1/2 or inability to penetrate bbb and exert central action on drn1 set