Flashcard sets with a 'methotrexate' term meaning 'antimetabolite, folate antagonist, enteres via active transport and inhibits folate synthesis, inhibits conversion of dihydrofolate to thfr, to depletion of thymidine, and decrease in dna/rna and protein. also becomes polyglutamated and accumulates in cells and increases inhibitory effects on enzymes involved in folate metabolism and increase in duration of action'

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See other definitions of term:methotrexate