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5 Written questions

5 Matching questions

  1. In positive control of several sugar-metabolism-related operons, the catabolite activator protein (CAP) binds to DNA to stimulate transcription. What causes an increase in CAP?
    A) increase in glucose and increase in cAMP
    B) increase in glucose and decrease in cAMP
    C) decrease in glucose and increase in cAMP
    D) decrease in glucose and increase in repressor
    E) decrease in glucose and decrease in repressor
  2. If you were to observe the activity of methylated DNA, you would expect it to
    A) have turned off or slowed down the process of transcription.
    B) induce protein synthesis by not allowing repressors to bind to it.
    C) be unwinding in preparation for protein synthesis.
    D) be very actively transcribed and translated.
    E) be replicating nearly continuously.
  3. Tumor-suppressor genes
    A) are frequently overexpressed in cancerous cells.
    B) do all of the above.
    C) can encode proteins that promote DNA repair or cell-cell adhesion.
    D) often encode proteins that stimulate the cell cycle.
    E) are cancer-causing genes introduced into cells by viruses.
  4. Which of the following is a protein produced by a regulatory gene? A) operon
    B) inducer
    C) corepressor
    D) repressor
    E) promoter
  5. Use the following information to answer the following questions.
    InDrosophila after ~100 minutes postfertilization, the embryo looks like the following diagram, with all nuclei having moved to the periphery and, subsequently, four of the nuclei being sequestered at the posterior end. The four sequestered cells at one end are most probably destined to become
    A) mouthparts.
    B) antennae.
    C) the legs of the adult fly.
    D) the germ cells of the adult.
    E) wing primordial.
  1. a D) the germ cells of the adult
  2. b C) decrease in glucose and increase in cAMP
  3. c C) can encode proteins that promote DNA repair or cell-cell adhesion
  4. d A) have turned off or slowed down the process of transcription
  5. e D) repressor

5 Multiple choice questions

  1. D) host cells lack enzymes that can replicate the viral genome
  2. D) no AUG in any frame
  3. D) to sequence a DNA fragment
  4. B) interference with new viral replication in preexisting cases
  5. C) mutation of existing viruses, the spread of existing viruses to new host species, and the spread of existing viruses more widely within their host species

5 True/False questions

  1. DNA microarrays have made a huge impact on genomic studies because they
    A) dramatically enhance the efficiency of restriction enzymes.
    B) can be used to eliminate the function of any gene in the genome. C) allow the expression of many or even all of the genes in the genome to be compared at
    once.
    D) allow physical maps of the genome to be assembled in a very short time.
    E) can be used to introduce entire genomes into bacterial cells.
    C) allow the expression of many or even all of the genes in the genome to be compared at once

          

  2. Some viruses can be crystallized and their structures analyzed. One such virus isDesmodium, or yellow mottle virus, which infects beans. This is a member of the tymovirus group and has a single-stranded RNA genome of ~6,300 nucleotides. Its virion is 25—30 nm in diameter, and is made up of 180 copies of a single capsid protein that self-associate to form each capsomere, which has icosahedral symmetry with 20 facets.
    If this virus has capsomeres with 20 facets, how many proteins form each one?
    A) 1
    B) ~6
    C) 5
    D) ~180
    E) ~20
    E) X inactivation in the embryo is random and produces different patterns

          

  3. As genetic technology makes testing for a wide variety of genotypes possible, which of the following is likely to be an increasingly troublesome issue?
    A) discrimination against certain racial groups because of major genetic differences
    B) the need to legislate for the protection of the privacy of genetic information
    C) using technology to identify genes that cause criminal behaviors D) alteration of human phenotypes to prevent early disease
    E) use of genotype information to provide positive identification of criminals
    D) Dicer enzyme has reduced it to smaller double-stranded pieces

          

  4. In recent times, it has been shown that adult cells can be induced to become pluripotent stem cells (iPS). In order to make this conversion, what has been done to the adult cells?
    A) Cytoplasm from embryonic cells is injected into the adult cells.
    B) An adenovirus vector is used to transfer embryonic gene products into adult cells.
    C) The nucleus of an embryonic cell is used to replace the nucleus of an adult cell.
    D) A retrovirus is used to introduce four specific regulatory genes.
    E) The adult stem cells must be fused with embryonic cells.
    D) A retrovirus is used to introduce four specific regulatory genes

          

  5. In order to identify a specific restriction fragment using a probe, what must be done?
    A) The fragments must be separated by electrophoresis.
    B) The fragments must be separated by electrophoresis, the fragments must be treated with heat or chemicals to separate the strands of the double helix, and the probe must be hybridized with the fragment.
    C) The fragments must be treated with heat or chemicals to separate the strands of the double helix.
    D) The probe must be hybridized with the fragment.
    E) The fragments must be separated by electrophoresis and the fragments must be treated
    with heat or chemicals to separate the strands of the double helix.
    B) The fragments must be separated by electrophoresis, the fragments must be treated with heat or chemicals to separate the strands of the double helix, and the probe must be hybridized with the fragment.