What are the pharmacological agents used for mechanically ventilated patients?
"Morphine sulfate is a narcotic analgesic and causes a decrease in respiratory rate and tidal volumes in high doses.
Valium/Versed /ativan /Conscious sedation procedure
Anti-anxiety , sedative, anticonvulsant, Acts on CNS for anxietry, relieves fear
Pavulon(Pancuronium Bromide)Non-depolarizing neuromuscular blocking agent
Causes total muscle relaxation
Takes 2-3 min , no cardiovascular effects. Reversed by anticholinesterase dreu Edrophonium Chloride(Tensilon)
Curare(d-Tubocurarine)Non-depolarizing neuromuscular blocking agent, causes muscle paralysis, Reversed by Neostigmine and Atropine(Neostigmine destroys acetylcholinesterase) Check for complete reversal by asking patient to move
Norcuron(Vecuronium bromide) Non-depolarizing neuromuscular blocking agent, more potent than Pancuronium Bromide, less likely to cause histamine release, onset 2.5 -3min, duration 25-40min
Anectine(succinylcholine chloride) Sucostoran, given primarily for intubation, Fast acting drug last 3-10minute"