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5 Written questions

5 Matching questions

  1. Negri bodies
  2. Viruses with animal vectors
  3. Viruses with wild mice vectors
  4. sylvan cycle for yellow fever
  5. Hemorrhagic fevers
  1. a High fever and bleeding are the primary symptoms
    -mortality rates can be as high as 80%
    -bleeding is due to multiple mechanisms depending on the virus
  2. b Rabies
  3. c Mosquito to monkey and back to mosquito
    -humans are incidental
  4. d Sin Nombre
  5. e Eosinophilic cytoplasmic inclusion body found in nerves and characteristic of rabies

5 Multiple choice questions

  1. -Killed vaccine for humans
    -live attenuated vaccine for animals
    -vaccine recommended for high-risk people (veterinarians, postexposure)
    -rabies immunoglobulin use for postexposure prophylaxis (must must must be started before patient is symptomatic)
  2. -Seen in Colorado tick fever
    -transmission pattern: small animals→ ticks→ other tics → back to small animals
    -humans are incidental
  3. -Diagnosis of lassa and Ebola are only done by reference centers in the CDc (requires BL4 containment lab)
    -hantavirus is diagnosed by serology
    -rabies is diagnosed using immunohistochemistry on autopsied brain tissue
  4. 1. Cultures are available for most of the Arboviruses
    -not routine
    -may involve inoculation of newborn mice
    2. diagnosis is usually made by serology using acute and convalescent sera
    -obtaining a sample can be troublesome
    -blood only contains virus during viremia
    -stool is negative
    -viruses rarely found in the throat or CNS
    3. PCR looks promising
  5. The incidence of infection is much higher than the number of people that develop clinical symptoms
    -for every person that develops West Nile encephalitis there are approximately 150 people who are infected

5 True/False questions

  1. Complexities of arbovirusesControl exposure to vector


  2. type of genome of all viruses spread by animal vectorsRNA


  3. Number of known survivors from rabiesControl exposure to vector


  4. arbovirus-Arthropod borne
    -can be transmitted by bloodsucking arthropods including tics, sand flies, and mosquitoes


  5. Mechanism of yellow fever hemorrhagic sequelaeVirus is shed into the feces of the tick and onto the skin of the human; itching introduces the contaminated feces into the host by breaking the skin barrier


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