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General overview of inflammation
Terms in this set (6)
A protective response involving host cells, blood vessels, and proteins and other mediators that is intended to eliminate the initial cause of cell injury, as well as the necrotic cells and tissues resulting from the original insult, and to initiate the process of repair.
What is the goal of the inflammatory response?
To bring leukocytes and plasma proteins to the site of tissue infection or tissue damage.
What characterizes acute inflammation?
- Fluid and plasma exudation
- Predominantly neutrophilic leukocyte accumulation
What characterizes chronic inflammation?
- Influx of lymphocytes and macrophages
- Vascular proliferation
- Fibrosis (scarring)
List the cardinal signs of inflammation
Calor - heat
Rubor - redness
Tumor - swelling
Dolor - pain
Functio laesa - loss of function
The steps of inflammation can be remembered by the 5 R's. What are they?
1. Recognition of the injurous agent
2. Recruitment of leukocytes
3. Removal of the agent
4. Regulation (control) of the response
5. Resolution (repair)
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