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35 terms

Hemostasis and coagulation- calvarez2

Term 1, Unified Exam 2, Margaret Anderson
STUDY
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_____ is the process that stops bleeding from a damaged blood vessel
hemostasis
Hemostasis is the process that _____
stops bleeding from a damaged vessel
Excessive bleeding and blood loss is called _____
hemorrhage
Hemorrhage is the opposite of _____
hemostasis
When a vessel is injured, processes are set in motion to _____
form a clot
Clot formation is called _____
coagulation
_____ is called coagulation
clot formation
A clot that is so large that it occludes a vessel is called a _____
thrombus
Thrombus is _____
a clot that occludes a vessel
A clot that is so unstable that it can be dislodged and occlude a vessel downstream is called _____
embolus
embolus
A clot that is so unstable that it is dislodged and occludes a vessel downstream
Clot formation must be accomplished WHILE _____
letting blood to continue to flow through the injured vessel during repair
When the wound to a vessel is repaired, a clot must be _____
dissolved
T or F:
Clotting and hemostasiscan maintain the integrity of a severed major artery
False:
A tourniquet must be applied to prevent excessive bleeding
Functions of plasma proteins
Contribute to colloid osmotic (oncotic) pressure, defend against foreign invaders, participate in blood clotting, are carriers for hormones and cholesterol and ions, serve as signaling molecules and extracellular enzymes or cytokines
Function of Albumins
Major contributors to oncotic pressure of plasma; carriers of various substances
Organ source of Albumins
Liver
Function of globulins
clotting factors, enzymes, antibodies, carriers for various substances
organ source of globulins
liver and lymphoid tissues
function of fibrinogen
forms fibrin threads essential to blood clotting
organ source of fibrinogen
liver
function of transferrin
iron transport
organ source of transferrin
liver and other tissues
hematopoiesis
synthesis of blood cells
When does hematopoiesis begin?
Hematopoiesis begins at about the 3rd week of embryonic development and continues throughout life
3 main types of blood cells:
Red blood cells, white blood cells, platelets
platelets AKA _____
thrombocytes
**In primary hemostasis, formation of the platelet plug requires
collagen because collagen gets exposed and then everything else gets activated
**What other molecules besides collagen are involved in primary hemostasis
Integrins, platelet aggregating factors
**Timing
...
mengiococcemia, niceria bacteria
...
treatment for meningicoccemia
protein C
Chemical Factors involved in coagulation
...
**plasminogen is incorporated into the clot, not _____
plasmin
tPA is released by the _____
damaged endothelium