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Immunohematology Antibody Chart

Describes ABY class, clinical significance, reaction phases, enzyme effect, and other features of antibodies
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Which ABYs are IgG?
-Rh (D, C, E, c, e)
-Kell
-Duffy
-Kidd
-S,s,U
Which ABYs are IgM?
-M,N
-P
-Lewis
Which phase(s) does Rh ABYs react?
-37C
-AHG
Which Rh ABY is the most antigenic?
Anti-D
Which phase(s) does Kell ABYs react?
AHG
Which ABY is the most antigenic next to Anti-D?
Kell
Which phase(s) does Duffy ABYs react?
AHG
Which ABY is associated with malaria?
Duffy
Which phase(s) does Kidd ABYs react?
AHG
Which ABY is associated with delayed transfusion reactions?
Duffy
Which phase(s) does M,N ABYs react?
-Initial Spin
-37C
-AHG
Which phase(s) does S,s,U ABYs react?
AHG
Which phase(s) does Lewis ABYs react?
-Initial Spin
-37C
Which ABY are lost during pregnancy?
Lewis
Which ABY is associated with African Americans?
Lewis b
Which AGNs are absorbed onto RBCs from plasma (rather than being produced by the RBCs)
Lewis
Which phase(s) does "P" ABYs react?
Initial Spin
Which phase(s) does "I" ABYs react?
Initial Spin
Which cold ABY is associated with M. pneumoniae infection?
Anti-I
Which cold ABY is associated with Infectious Mononucleosis?
Anti-i
What is the enzyme effect on Rh ABYs?
Enhanced
What is the enzyme effect on Kell ABYs?
No Effect
What is the enzyme effect on Duffy ABYs?
Destroyed
What is the enzyme effect on Kidd ABYs?
Enhanced
What is the enzyme effect on MNS ABYs?
Destroyed
What is the enzyme effect on Lewis ABYs?
No Effect
What is the enzyme effect on "P" ABYs?
No Effect
What is the enzyme effect on "I" ABYs?
No Effect
Which ABYs are enhanced by enzymes?
-Rh
-Kidd
Which ABYs are destroyed by enzymes?
-Duffy
-MNS
Which ABYs are clinically significant?
IgG
Which ABYs are NOT clinically significant?
IgM
Which ABYs can be neutralized?
-Lewis a
-Lewis b
-P1
Which enzymes are used to enhance or destroy ABYs on a panel?
-Papain
-Ficin