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15 terms

Chapter 18: Adrenergic Drugs

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Adrenergic agonist
drugs that stimulate and mimic the actions of the sympathetic nervous system; also called sympathomimetics
Adrenergic receptors
receptor sites for the sympathetic neurotransmitters norepinephrine and epinephrine
Alpha-adrenergic receptors
a class of adrenergic receptors that are further subdivided into alpha1- and alpha2-adrenergic receptors, and are differentiated by their anatomic location in the tissues, muscles, and organs regulated by specicific autonomic nerve fibers
Autonomic functions
bodily functions that are involuntary and result from the physiologic activity of the ANS. the functions often occur in pairs of opposing actions b/w the sympathetic and parasympathetic divisions of the ANS.
Autonomic Nervous System
a branch of the PNS that controls autonomic bodily functions; it ocnsists of the sympathetic nervous system and the parasympathetic nervous system
Beta-adrenergic receptors
receptors located on postsynaptic effector cells of tissues, muscles, & organs stimulated by specific autonomic nerve fibers.
Catecholamines
substances that can produce a sympathomimetic response. they are either endogenous catecholamines or synthetic catecholamine drugs
Dopaminergic receptor
a 3rd type of adrenergic receptor located in various tissues and organds and activated by the binding of the neurotransmitter dopamine, which can either be endogenous or a synthetic drug form
Mydriasis
pupillary dialtion, whether natural (physiologic) or drug induced
Ophthalmics
drugs that are used in the eye
Positive chronotropic effect
an increase in heart rate
Positive dromotropic effect
an increase in the conduction of cardiac electrical impulses thru the AV node, which results in the transfer of nerve action potentials from the atria to the ventricles. this ultimately leads to a systolic heartbeat
Positive inotropic effect
an increase in the force of contraction of the heart muscle
Sympathomimetics
drugs used therapeutically that mimic the catecholamines epinephrine, noeepinephrine, and dopamine; also called adrenergic agonists
Synaptic cleft
the space either b/w 2 adjacent nerve cell membranes or b/w a nerve cell membrane and an effector organ cell membrane (synapse)