- pulmonary edema, renal failure, abruption- placentae, disseminated intravascular coagulation, persistent cerebral symptoms, non-reassuring fetal testing, or fetal demise (women with these should be delivered regardless of gestational age)
- other CI: inability to control blood pressure with maximum doses of two antihypertensive medications, non-reassuring fetal surveillance, liver function test elevated more than two times normal, eclampsia, persistent CNS (central nervous system) symptoms and oliguria.
Acute fatty liver almost always manifests late in pregnancy. Symptoms develop over several days to weeks and include malaise, anorexia, nausea and vomiting, epigastric pain, and progressive jaundice. In many women, persistent vomiting in late pregnancy is the major symptom. About half of all women have hypertension, proteinuria, and edema signs suggestive of preeclampsia. There is usually severe liver dysfunction with hypofibrinogenemia, hypoalbuminemia, hypocholesterolemia, and prolonged clotting times. As acute fatty liver worsens there is marked hypoglycemia. -hair-bearing skin and scalp, nails, oral mucous membranes and vulva.
- inflammatory mucocutaneous eruptions characterized by remissions and flares.
- Vulvar symptoms include irritation, burning, pruritus, contact bleeding, pain and dyspareunia.
-findings vary with a lacy, reticulated pattern of the labia and perineum, with or without scarring and erosions as well. With progressive adhesion formation and loss of normal architecture, the vagina can become obliterated. Patients may also experience oral lesions, alopecia and extragenital rashes
- TX: topical superpotent corticosteroids
- osteoperosis, elvated cholesterol and carottene levels, prolonged qt (arrythmias), euthyroid sick syndrome, hpa axis dysfunction resulting in anovluation, amenorrhea and estrogen deficiency, hyponatermia secondary tp excess water drinking
- babies may be SGA, misscarriage, hyperemesis gravidarum, c -section and post partum depresion, IUGR