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HIV (lower resp tract infections)

S. pneumonia, S. aureus, H. influenzae, gram-neg rods

HIV (noninfectious)

Kaposi sarcoma, non-Hodgkin lymphoma

HIV (CD4+ > 200)

bacterial/TB infections

HIV (CD4+ < 200)


HIC (CD4+ < 50)

CMV, mycobacterium

lung transplantation (indications)

end-stage emphysema,
idiopathic pulm fibrosis, idiopathic/famialial pulm arterial HTN

lung transplantation (complications)

infection, rejection

lung transplant (pulm infection)

1st few weeks - bacterial
fungal - Candida, Asperigillus

lung transplant (acute rejection)

early weeks to months
fever, dyspnea, cough, infiltrates

lung transplant (acute rejection, morph)

inflamm infiltrates (lympho, plasma cell, few neutro/eosino) - small vessels/submucosa of airways

lung transplant (chronic rejection)

3-5 years after
cough, dyspnea, irreversible ↓LFT bronchiolitis obliterans

lung transplant (chronic rejection, morph)

bronchiolitis obliterans (patchy)
long-term - bronchiectasis, pulm fibrosis

bronchiolitis obliterans

partial/complete occlusion of small airways by fibrosis

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