nicotinic receptors (nAChR)
or nAChRs, are cholinergic receptors that form ligand-gated ion channels in the plasma membranes of certain neurons. Like the other type of acetylcholine receptors - muscarinic acetylcholine receptors (mAChRs) - the nAChR is triggered by the binding of the neurotransmitter acetylcholine (ACh). However, whereas muscarinic receptors are also activated by muscarine, nicotinic receptors are also opened by nicotine. Hence, the name "nicotinic".
depolarized the membrane of excitable cells and opens voltage gated ion channels
bind to ACh and open channels; are found on glands at every synapse of the sympathetic nervous system