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GI bladder stimulant, xerostomia (dry mouth)

methacholine (Provocholine)

asthma diagnosis

direct cholinergic choline esters and congeners

ACh, methacholine, carbachol, bethanechol

direct cholinergic alkaloids

muscarine, pilocarpine

indirect reversible cholinesterase inhibitors

physostigmine (eserine), neostigmine, pyridostigmine

physostigmine (eserine)

reversible AChase inhibitor, no quat. structure, penetrates into CNS


Dx: myasthenia gravis


protection against organophosphate gases, Tx: myasthenia gravis

CNS selective cholinesterase inhibitors

donepezil, tacrine (Cognex), rivastigmine, galantamine

Indirect irrever. AChase inhibitors

organophosphates, phosphate esters, echothiophate


parathion, malathion

war gases

tabun, soman, sarin

irrever. AChase inhibitor antidote

atropine + pralidoxime (2-PAM)

slowly reversible AChase inhibitors

sevin (Carbaryl)

slowly rev. Achase inhibitor antidote

atropine + support

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