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60 terms

Viruses and diseases

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Adenovirus
respiratory infection, conjunctivitis
Parvovirus
B19 (fifth disease/erythema infectiosum, fetal death, aplastic crisis)
Reoviridae
Rotavirus (infantile gastroenteritis)
Filoviridae
Ebola virus (ebola), marburg virus
Paramyxoviridae
Parainfluenza virus; Mumps virus; Respiratory syncytial virus; Morbillivirus (mumps); Pneumovirus; Metapneumovirus
Orthomyxoviridae
Influenza A, B and C
Picornaviridae
Enterovirus (Poliovirus, coxsackie A and B, echovirus, enterovirus), Rhinovirus, Heparnavirus
Caliciviridae
Norwalk (gastroenteritis)
Flaviviridae
Yellow fever virus (yellow fever); Hepatitis C (hepatitis)
Togaviridae
Eastern Equine encephalitis virus (encephalitis); Rubella virus (rubella)
HSV-1
Cold sores, encephalitis
HSV-2
Herpes genitalis, meningitis
reactivation of varicella-zoster virus
Herpes zoster, herpes zoster ophthalmicus
Epstein-Barr virus
Infectious mononucleosis
Cytomegalovirus
congenital (birth defects, low birth weights, microcephaly), STD, blood/organ transplants, immunosuppressed patients
Human herpesvirus 6 and 7
Exanthem subitum (Roseola) in children and in AIDS patients
Human herpesvirus 8
Kaposi-Sarcoma-Associated Herpesvirus
Poxvirus
Molluscum contagiosum, smallpox
Picornavirus
Poliomyelitis (polio)
Rhinovirus
common cold
Coxsackievirus A16
Hand-foot-and-mouth disease
Coxsackievirus A
herpangina
Coxsackievirus B
Myocardial or pericardial infection (high mortality)
Coxsackievirus or echovirus
viral meningitis
Norovirus
food-borne gastroenteritis; cruise ships
Parainfluenza virus
croup
Coronavirus
SARS, common cold
Respiratory syncytial virus
bronchiolitis and pneumonia in infants and children
Mumps virus
•Epidemic parotitis; painful swelling of parotid
salivary glands
•Humans = only reservoir.
•Long-term immunity.
•Live attenuated vaccine MMR
Morbillivirus
Mumps, measles
Paramyxoviruses
distemper virus in dogs and seals; morbillivirus in dolphins and porpoises; Newcastle disease virus (birds); Rinderpest virus (cows)
Henipavirus
zoonotic, reservoir is fruit bats
Henipavirus (paramyxoviridae family)
Hendra virus (HeV) and Nipah virus (NiV)- biosafety level 4
Pneumovirus
Respiratory syncitial virus (RSV; bronchiolitis and pneumonia) and Metapneumovirus (colds, bronchiolitis, and pneumonia)
Metapneumovirus
colds, bronchiolitis, and pneumonia
Influenza
respiratory symptoms and the classic
flulike symptoms of fever, malaise, headache and
myalgias
Rhabdovirus
rabies
Ebola virus
widespread tissue necrosis; endothelial damage leads to vascular injury and bleeding; hemorrhage leads to hypovolemic shock; severe hemorrhagic fever; fatal in 90% of infections
Rotavirus
Human infantile gastroenteritis- endemic, severe
diarrheal illness
Flavivirus
Yellow fever, West Nile encephalitis
Arbovirus
Flavivirus and togavirus
Flavivirus
Hepatitis C virus
Togavirus
Rubivirus (cause of rubella)
Yellow fever
high fever, yellowing of skin and eyes, coffee-ground emesis, severe liver damage, severe renal tubule damage; mosquito vector; "re-emerging disease"
Togavirus
Western and Eastern equine encephalitis (WEE and EEE)
Western and Eastern equine encephalitis (WEE and EEE)
low-grade, flulike symptoms; can progress to encephalitis; resolves spontaneously; mosquito vector
Flavivirus
West Nile virus
West Nile virus
Headache, Fever, Rash, Fatigue, Weakness; rare cause of encephalitis and paralysis; mosquito vector
Bunyavirus
California encephalitis; Rift Valley fever; Korean hemorrhagic fever; American _____ = hantavirus, A.K.A. Sin Nombre - emerging disease
Arenavirus
Lassa fever, Argentine hemorrhagic fever, Bolivian
hemorrhagic fever, and Lymphocytic choriomeningitis
Hepatitis A Virus
causes jaundice in high percentage of cases; oral-fecal route; spread in daycare; no chronic infection
Hepatitis B Virus
the only DNA virus; transmitted via blood, STD; causes chronic persistent and active hepatitis; leads to hepatocellular carcinoma and cirrhosis of liver
Hepatitis C Virus
transmitted via blood; no protective antibody response identified; leads to chronic persistent hepatitis, chronic active hepatitis, cirrhosis, and hepatocellular carcinoma but less than HBV
Hepatitis D Virus
similarity to viroids in plants; coinfection and superinfection with HBV; transmitted sexually and through blood
Hepatitis E Virus
calicivirus-like; transmitted through fecally contaminated drinking water
Prions
Causes transmissible spongiform
encephalopathies (TSEs) in humans and
animals and neurodegenerative diseases with long
incubation periods
Prions
Kuru, Creutzfeldt-Jakob Disease (CJD), and Variant CJD (vCJD)
Creutzfeldt-Jakob Disease (CJD)
alteration in the structure of normal PrP protein found in the brain that results in nerve cell death, spongiform damage, and severe loss of brain function
Papillomavirus
warts
Polyomavirus
BK and JC viruses; associated with renal disease (BK) and progressive multifocal leukoencephalopathy, aka PML (JC) in immunosuppressed people