25 terms

Cecil - Chp 17 - 02

bronchiolar disorders
patchy inflammation/epithelial injury, fibrosis of bronchioles (noncartilaginous)
acute bronchiolitis
bronchiolitis obliterans syndrome
after lung transplantation
diffuse panbronchiolitis
in Japan, cough w/ purulent sputum
bronchiolar disorders (diagnosis)
HRCT (tree-in-bud opacities)
bronchiolitis obliterans syndrome (treatment)
abn dilation of bronchi (inflamm/destruction bronchial walls)
bronchiectasis (cause)
bacterial, viral, allergic bronchopulmonary aspergillosis
Kartagener syndrome
clinical triad (sinusitis, situs inversus, infertility)
bronchiectasis (younger pts)
cystic fibrosis, primary ciliary dyskinesia
bronchiectasis (clinical)
chronic cough, foul-smelling sputum
bronchiectasis (radio)
tram track shadows (thickened bronchial walls)
cystic fibrosis
autosomal recessive, multi-organ (lung, pancrease, repro), CFTR defect
CTFR mutation
defective chloride transport, ↑Na absorp (airway, thick mucus) exocrine dysfunction
cystic fibrosis (clinical)
meconium ileus, steatorrhea, salty-tasting skin, pancreatic insufficiency, malasborption, azoospermia
advanced cystic fibrosis
multidrug resistant Burkholderia cepacia
cystic fibrosis (diagnosis)
sweat test > 60 mEq/L (chloride, two occasions)
cystic fibrosis (treatment)
pancreatic enzy replacement, antibiotics, bronchodilators, dornase alfa (sputum), inhaled tobramycin (pseudomal)
airway inflammation, airway hyper-reactivity, reversible airflow obstruction
asthma (immune system)
TH2-predominant T-cell response
asthma (hallmark)
airway hyperresponsiveness
asthma (pathogenetic mechanism)
airway inflammation
airway wall remodeling
hyperplasia/trophy smooth m cells, deposition collagen type I/III (thickening)
asthma (clinical)
triad (wheezing, chronic episodic dyspnea, chronic cough), pulsus paradoxus
asthma (diagnosis)
diaphoretic↓FEV1, bronchoprovocation challenge (methacholine, cold-air)