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from bone marrows, in circluation, also in lymph fluid, nodes and spleen, [secondary lymphoid organs]
macrophages and monocytes
in tissue, roam under skin, left circulation, always migrate to site of infection
basophils and mast cells
Migrate to sources of infection, active in hypersensitivity and allergic reactions
Antigen-presenting cells, located mainly in lymphatic tissues and skin, that is particularly efficient in presenting antigens to naive helper T cells, thereby initiating a primary immune response.
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