Internal Secretions (hormone) produced by a ductless gland that secretes directly into bloodstream. Includes: Natural or Synthetic.
Location base of brain called Master Gland bc it regulates the function of other glands. Secretes sevreal homrones: Somatotropin & ACTH
Location adjacent to kidneys. Secrete hormones called CORTICOSTERIODS act on immune system to supress the bodys response to infection or trauma. They relieve inflammation, reduce swelling, & supress sysmptoms in acute conditions.
Corticosteriods 2 Broad Categories
1. Replacement therapy when secretions of pituitary or andrenal gland are deficient. 2. Antinflammatory & immunosupressenat properties.
Coritcosteriods not curative but supporitve thearpy with other meds. Conditions treated:
Allerigic reactions - Acute flare ups: rhemuatic, collagen, skin, disorders Malignancies: leukemia, lymphoma, hodgkins. Cerebral edema: brain tumors & neurosurgery Organ Transplant: to prevent rejection Life-threatening shock: adrenocortical insufficiency Acute Flare-ups: ulcers, short term avoid hemorrhag
Corticosteriods Patient Education
Never stop taking med abruptly. Report S/S of infection or within 12 months after therapy is discontinued. Take oral with or STAT after meal. Mutliple doses spaced out during day. Single dose before 9am SE: long term fluid retention & edema Dangers of infection, delayed wound healing, osteoporsis, mental disorders.
Used in replacement therapy for HYPOTHYROIDISM caused by absent thyroid function. Its causes slow metabolism, fatigue, dry skin, thinning of hair, weight gain, sensitivity to cold, irregular menses.
Weight loss with use of Thyroid Agents
When thyroid function is normal is contrainindicated, ineffective, & dangerous, leading to decrease in nomral thyroid function & life threatening cardiac arrhythmias.