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Death from a TCA is usually due to what?
V-fib and/or cardiogenic shock (inhibits cardiac fast NA channels)
medication for atrail fibrillation that can cause heart block and constipation?
Ca channel blocker (verapamil, -dipines, diltiazem)
class of drug to treat dry mouth, flushed skin, dilated pupils that are non-reactive to light after being outdoors?
long acting benzos?
CCDF (The bad grades for older people) chlordiazepoxide, clorazepate, diazepam, flurazepam
how do -afils affect vascular smooth muscle?
inhibit PDE blocking metabolism of cGMP (NO causes an increase in cGMP - reason why nitrates with PDE inhibitors cause problems)
what antiarrhythmic modulates phase 1 of the ventricular action potential?
none (Na influx slows; K permeability increases)
what antiarrhythmic modulates phase 2 of the ventricular action potential?
Class IV (Ca influx and minimal K efflux- so Class 3 has minor influence)
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