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Poxvirus, papillomarviruses, and African swine fever
Terms in this set (56)
Tularemia, Plaque, and herpes virus are differentials for what?
What do we use for a conclusive diagnosis?
Target: ______ gene?
What virus is linked to prairie dogs?
does everyone get a poxvirus?
Are capripoxvirus and leporipoxvirus notable diseases?
What is the largest virus?
Pox virus has a ____/___ structure?
Is poxvirus enveloped?
Poxvirus: where does intermediate gene expression and DNA replication occur?
What has fusion/macropinocytosis, uncoating and early protein synthesis, late phase gene expression, viral assembly, intracellular mature virion and external enveloped virion?
How long is the incubation period of poxvirus?
what kind of skin lesions are seen in poxvirus?
vesicles and scabbing
What 3 things help poxvirus with its immunity?
IFN-directed, complement cascade, and CTL-mediated
How does poxvirus evade the immune system?
stealth and mimicry
What virus uses MHC 1, CD4 depletion/down regulation, IFN & TNF receptor homologs, IL-10 homologs, and complement system to evade the immune system?
What 2 poxvirus has a worldwide distribution, oronasal lesions, is zoonotic and recovery usually in about 3 weeks?
bovine papular stomatitis and orf/contagious ecthyma
What poxvirus is a FAD, dermal/pulmonary, 50% mortality, MLV and subunit vaccine?
Where is sheep/goatpox found?
africa and asia
What poxvirus is an FAD, endothelial damage, 5% mortality rate, high economic loss, MLV and subunit vaccines?
lumpy skin disease
Where is lumpy skin disease found?
africa and asia
What poxvirus is mostly found in australia?
What poxvirus has 25-99% mortality, MLV, non-lethal analog virus, and lymphocytes are targeted?
In myxomatosis are the sylvilagus or oryctolagus affected?
How is poxvirus transmitted? (4)
aerosol, vector, direct contact, fomite
How do we treat poxvirus?
prevention and control of poxvirus: ____ where available, control mechanical ____ and isolate and prevent ___?
vaccination, vectors, contact
____ are pox virions released from lysed cells, while ____ are those that bud from the membrane?
Differentials for dermal neoplasias on a stud farm are equine _____, ____ cell _____, _____ and ____ dermatitis?
sarcoid, squamous cell carcinoma, granulomas, solar
What samples would we collect for dermal neoplasia on a stud farm?
What tests would we want to run from samples of dermal neoplasia on a stud farm?
Derma neoplasia on a stud farm: histology shows spindle cells in interlacing bundles and whorls, collagenous matrix, and low-moderate mitotic rate, which means what?
What is the putative etiology for equine sarcoids?
is papillomarvirus enveloped?
is papillomarvirus small?
papillomarvirus is ___ shaped?
papillomarvirus: ____ within basal squamous epithelial cells, transport to the ____, early and late protein transcription/translation, and +/- host chromosome integration?
papillomarvirus has a lengthy and variable what?
In papillomarvirus what kind of lesions are on the epithelium?
What 3 places are papillomarvirus found?
Dermis, oral/gastric mucosa, and bladder
Immunity of the papillomarvirus is primarily what?
What 2 things help the papillomarvirus evade the immune system?
Stealth and IFN pathway inhibition
papillomarvirus has no ____ and is non-____?
What are 3 ways to treat papillomarvirus?
excision, cryosurgery, radiation/chemo
Is there prevention for papillomarvirus?
Where does papillomarvirus replication occur?
What is the only known DNA virus with an arthropod vector?
african swine fever
Is african swine fever enveloped?
Is african swine fever an FAD?
What shape is african swine fever?
African swine fever: viral _____, viral fusion and DNA release into the ____, early gene transcription and genome replication, late gene transcription, packaging, and membrane budding?
What has a heavy load in transmitting african swine fever?
African swine fever is mostly contained in ___, but has spread to western ___?
Clinical signs of african swine fever:
Peracute: _____ ____
Acute: fever ADR, and cutaneous _____
Subacute: ______, weight loss, joint ___, ADR
sudden death, hemorrhage, pneumonia, swelling
What stage of african swine fever has a high mortality?
Treatment and prevention of african swine fever includes ____/____/___, prevent exposure to wild or feral ___, ___vectors, minimally effective ___ and ____ incompatible?
depop, clean, repop, swine, insect, vaccine, DIVA
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