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Penicillin was considered a "miracle drug" for all of the following reasons EXCEPT
It was the first antibiotic
Which one of the following does NOT belong with the others?
The antibiotic tetracycline binds to the 30S subunit of the ribosome as shown in Figure 20.1. The effect is to
Prevent peptide bond formation
The antibiotic cycloheximide binds to the 60S subunit of the ribosome as shown in Figure 20.2. The effect is to
Prevent polypeptide elongation in eukaryotes
Which of the folllowing antibiotics is recommended for use against gram-negative bacteria?
Which of the following antimicrobial agents is recommended for use against fungal infections?
The antibiotic chloramphenicol binds to the 50S subunit of the ribosome as shown in Figure 20.3. The effect is to
Prevent attachment of tRNA
The antibiotic streptomycin binds to the 30S subunit of the ribosome as shown in Figure 20.4. The effect is to
Cause misreading of mRNA in 70S ribosomes
Which of the following antibiotics are used to treat fungal infections?
Which of the following statements is false?
A. Fluoroquinolone inhibits DNA synthesis
B. Acyclovir inhibits DNA synthesis
C. Amantadine inhibits release of viral nucleic acid
D. Interferon inhibits glycolysis
E. Azoles inhibit plasma membrane synthesis
Interferon inhibits glycolysis
Protozoan and helminthic diseases are difficult to treat because
Their cells are structurally and functionally similar to human cells
Which of the following organisms would most likely be sensitive to natural penicillin?
Which of the following statements about drug resistance is false?
It is found only in gram-negative bacteria
Which of the following does NOT constitute an advantage of using two antibiotics together?
Two are always twice as effective as one
In Table 20.2, which antibiotic would be most useful for treating a Salmonella infection?
Which of the following would be selective against the tubercle bacillus?
Ethambutol - inhibits mycolic acid synthesis
Lamisil is an allylamine used to treat dermatomycoses. Lamisil's method of action is similar to that of
Niclosamide prevents ATP generation in mitochondria. You would expect this drug to be effective against
Which of the following statements about drugs that competitively inhibit DNA polymerase or RNA polymerase is false?
They are too dangerous to use
The substrate for transpeptidase used to synthesize peptidoglycan is shown in Figure 20.5. Which of the drugs shown would inhibit peptidoglycan synthesis?
Horizontal beginning with hexagon
The structures of the influenza drug Tamiflu and sialic acid for influenza virus' neuramidase, are shown in Figure 20.6. What is the method of action of Tamiflu?
Mebendazole is used to treat cestode infections. It interferes with microtubule formation; therefore, it would NOT effect
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