Create an account
Insulin (Islet β cell)
Decreases serum glucose level; Promotes utilization of glucose & lipid synthesis
HLA linked genes
genes that are involved in immune tolerance and regulation; leads to development of autoimmunity
Accumulation of acidic ketone bodies in blood due to lack of insulin stimulated fatty acid utilization
thickening of basement membranes of small vessels, important morphological feature that is responsible for
improves glucose tolerance in patients w/ type 2 diabetes; Decreases intestinal absorption of glucose; Improves insulin sensitivity by increasing peripheral glucose uptake & utilization
Secondary DM due to
Diseases that destroy pancreatic islet cells; Endocrine disorders where effect of insulin is antagonized; Drugs
Diseases that destroy pancreatic islet cells
pancreatitis, cystic fibrosis, iron overload (hemochromatosis), surgical removal of pancreas
Endocrine disorders where effect of insulin is antagonized
GH excess (acromegaly), Cushing syndrome, exogenous CS intake
Please allow access to your computer’s microphone to use Voice Recording.
Having trouble? Click here for help.
We can’t access your microphone!
Click the icon above to update your browser permissions and try again
Reload the page to try again!Reload
Press Cmd-0 to reset your zoom
Press Ctrl-0 to reset your zoom
It looks like your browser might be zoomed in or out. Your browser needs to be zoomed to a normal size to record audio.
Please upgrade Flash or install Chrome
to use Voice Recording.
For more help, see our troubleshooting page.
Your microphone is muted
For help fixing this issue, see this FAQ.
Star this term
You can study starred terms together