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What is connective tissue important for?

support and protection

What are the four subclasses of connective tissue?

connective tissue proper, cartilage, bone, and blood

Common origin

arise from mesechyme


embryonic tissue

degree of vascularity

range from no blood vessels to rich supply

extracellular matrix

much of the connective tissue is made of nonliving extracellular matrix

How does extracellular matrix support tissue?

it seperates living cells in the tissue and allows connective tissue to bear great weight and tension and withstand abuse

What are three major components of connective tissue?

ground substance, fibers, and cells

What makes up the extracellular matrix?

ground substance and fibers

What does ground substance do?

fills the space between the living cells of a connective tissue and holds fluid and acts as a fluid medium for diffusion from blood vessels to occur

What is the structure of ground substance

unstructured and gel like

What is ground substance made out of?

interstial fluid, cell adhesion proteins, and proteoglycans

What are cell adhesion proteins?

acts as a glue to hold living cells to a matrix

What are proteoglycans?

substances that contain polysaccharides known as GAGs, the more GAGs in the matrix, the stiffer it is

What does ground substance hold?


What do fibers do?

provide support

What are the three types of fibers?

collagen fibers, elastic fibers, reticular fiber

collagen fibers

most abundant, form fibers in extracelluar matrix, very TOUGH and STRONG

elastic fiber

formed from protein elastin STRETCHY allows stretching of connective tissue like in skin, llungs, and blood vessel walls

reticular fibers

delicate fibers of collagen, provides support for soft tissue


each type of connective tissue hold fundamental cell type, immature and growing they secrete ground substances and fibers and divide rapidl, the "blast" stage


immature stage


mature stage

connective tissue proper

fibroblast, fibrocyte


chondroblast, chondrocyte


osteoblast, osteocyte


hemocytoblast (always activ)

fat cells in connective tissue

white blood cells, plasma cells, mast cells, macrophage

plasma cells

produce antibodies

mast cells

detect foreign substances, release substances to initiate inflmattory respons


large phagocytic cells, eat bacteria, dust, dead tissue cells, main players in immune system

what are the differences in the different types of connective tissue

cell types, fiber types, and proportion of extracellular matrix

what do all connective tissue have in common?

mesemchyme, as embryo develops, mesemchyme cells differentiate into different types of connective tissue

connective tissue proper

all connective tissue belongs to this except bone cartilage and blood

what are the two subclasses of connective tissue proper

loos connective tissue and dense connective tissue

what are the three types of loose connective tissue

they have few fibers; areolar, adipose, and reticular

what are the types of dense connective tissue

packed with fibers; dense regular, dense irregular, and elastic

what are the cells called in areolar connective tissue


what does areolar connective tissue serves as

packaging materian for organs and other tissues, holds water, and soaks up excess fluid in inflamed areas, and caused swelling edema


basically areolar connective where the nutrients storing function is greatly enhanced, fat cells called adipocytes present, every cell stores a nutrient rich oild droplet,

what percentage of an average person is fat cells


reticular connective tissue

reticular fibers are present

what do the fibers in reticular connective tissue form

delicate network called stromma in the spleen and lymph nodes which support free blood cells in these structures

dense regular

lots of collagen fibers, giving great resistance to tension, fibers run in one direction

which type of dense connective tissue forms tendons and ligaments

dense regular


bones to muscles


bone to bone

elastic connective

ligaments containg lots of elastic fivers, stretch

dense irregular connective tissue

fibers arranged irregulary, not all in one direction

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