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5 Written questions

5 Matching questions

  1. oral hypoglycemics
  2. TCAs
  3. nonbenzodiazepine, nonbarbiturate CNS depressants
  4. antimetabolites
  5. mood stabilizers
  1. a anticholinergic effects. tachycardia, tendency to cause urinary retention in men with prostate disorders, drowsiness, blurred vision, dry mouth, dry mucous membranes, urinary hesitancy, decreased sweating, orthostatic hypotension, sedation, constipation
  2. b fatal bone marrow toxicity at high doses. hemorrhage and bruising due to low platelet counts are often observed. Nausea, vomiting, and anorexia are common.
  3. c rashes and photosensitivity are possible. mild, GI-related effects such as nausea, vomiting, or loss of appetite
  4. d daytime sedation, confusion, amnesia, dizziness, depression, nausea, vomiting, headache, drowsiness, sweating, palpitations, shaking, rebound insomnia when discontinued
  5. e excessive sweating or dehydration can cause lithium toxicity. dizziness, fatigue, short-term memory loss, increased urination, nausea, vomiting, loss of appetite, abdominal pain, diarrhea, dry mouth, muscular weakness, and slight tremors

5 Multiple choice questions

  1. major dose-limiting adverse effect is bone marrow suppression. adverse effects are similar to those of the alkylating agents
  2. no serious adverse effects. Mild GI upset, diarrhea, and abdominal pain are most common.
  3. depress CNS function, drowsiness, withdrawal syndrome is extremely severe and can be fatal. overdose results in profound respiratory depression, hypotension, and shock. at high doses some can produce anesthesia
  4. orthostatic hypotenstion, headache, insomnia, diarrhea. avoid foods containing tyramine and caffeine
  5. GI disturbances. constipation, bloating, nausea, indigestion. self-medication with niacin can cause gout and liver damage from high doses. it will not lower cholesterol at low doses. take 1 hour before or 4 hours after other meds. dissolving it in water and keeping fluid intake high helps to avoid irritation of the mouth and constipation

5 True/False questions

  1. thrombolyticslike anticoagulants, bleeding is major adverse effect.

          

  2. biologic response modifiersdrowsiness, sedation, amnesia, weakness, disorientation, ataxia, sleep disturbance, BP changes, blurred vision, double vision, nausea, and vomiting.

          

  3. antifungal drugsBLEEDING.

          

  4. H1 receptor blockers (antihistamines)major dose-limiting adverse effect is bone marrow suppression. adverse effects are similar to those of the alkylating agents

          

  5. anticoagulantsBLEEDING.