Common Digitalis Glycosides
Toxic serium levels over 1.8-2ng/ml
Need to check apical hr for one full minute prior to admin.
not given if hr is<60bpm
Digitalis Glycosides Action
Increase the myocardial contraction-which increase cardiac output and is a Positve inotropic effect
and Slow ellectrical activity in the heart which decreses HR which is a negative chronotropic effect. Combined the two effects produce more forceful contractions and allow for greater effeciency.
Digitalis Glycosides SE
anarexia, vision (halos) and severe bradycardia-can be fatal. If pt has toxic level administer Digoxin immune fab (Ovine) iv. rapid onset >1 minute
Ace Inhibitors Action
Lower bp and decrease bv, this increases cardiac output
decrases rpload and reduces peripheral edema.